{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T21:42:17Z","timestamp":1777498937734,"version":"3.51.4"},"reference-count":0,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clinical Hemorheology and Microcirculation"],"published-print":{"date-parts":[[2013,8]]},"abstract":"<jats:p>\n                    OBJECTIVES: As most clinical studies measure whole blood viscosity (WBV) from peripheral samples, potential differences in WBV obtained from the coronary arteries are often ignored. This study investigated differences in WBV measured from coronary artery specimens in patients with and without acute coronary syndrome (ACS). METHODS AND RESULTS: Consecutive patients with chest pain who underwent diagnostic coronary angiography were divided into two groups [non-ACS (n = 16), ACS (n = 22)]. The ACS group consisted of unstable angina (n = 13) and acute myocardial infarction (n = 9) patients. Two blood samples were obtained from each patient at the both coronary artery ostia prior to coronary angiography. Low-shear and high-shear blood viscosities (BVs) were measured at shear rates of 1 and 300 s\n                    <jats:sup>\u22121<\/jats:sup>\n                    , respectively, by a scanning capillary tube viscometer (Bio-Visco Inc., SouthKorea). Both low-shear and high-shear BVs obtained from peripheral, left and right coronary arteries were not different in both groups. Mean coronary low-shear WBV values obtained in ACS group were 29.2% higher than those in non-ACS group (295.3 \u00b1 87.2 mP vs. 228.5 \u00b1 69.2 mP, p = 0.016). Mean coronary high-shear WBV values obtained in ACS group were 15.6% higher than those in non-ACS group (42.9 \u00b1 10.0 mP vs. 37.1 \u00b1 4.6 mP, p = 0.036). CONCLUSIONS: Direct measurement of WBV from the coronary artery showed no differences with peripheral samples. Future larger studies are needed to clarify our results.\n                  <\/jats:p>","DOI":"10.3233\/ch-131692","type":"journal-article","created":{"date-parts":[[2019,12,2]],"date-time":"2019-12-02T13:30:04Z","timestamp":1575293404000},"page":"85-94","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":13,"title":["Elevated coronary whole blood viscosity in acute coronary syndrome patients"],"prefix":"10.1177","volume":"55","author":[{"given":"Sang-Rok","family":"Lee","sequence":"first","affiliation":[{"name":"Division of Cardiology, Chonbuk National University Hospital, Jeonju, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin-Mu","family":"Jung","sequence":"additional","affiliation":[{"name":"Department of Mechanical Engineering and Mechanics, Drexel University, Philadelphia, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lae-Young","family":"Jung","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Chonbuk National University Hospital, Jeonju, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ju-Hyung","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine, Chonbuk National University Hospital, Jeonju, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sun-Hwa","family":"Lee","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Chonbuk National University Hospital, Jeonju, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyoung-Suk","family":"Rhee","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Chonbuk National University Hospital, Jeonju, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jei Keon","family":"Chae","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Chonbuk National University Hospital, Jeonju, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Won Ho","family":"Kim","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Chonbuk National University Hospital, Jeonju, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jae Ki","family":"Ko","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Chonbuk National University Hospital, Jeonju, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dong-Hwan","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Mechanical Engineering and Mechanics, Chonbuk National University, Jeonju, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert S.","family":"Rosenson","sequence":"additional","affiliation":[{"name":"Mount Sinai Heart, Mount Sinai School of Medicine, New York, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2013,1]]},"container-title":["Clinical Hemorheology and Microcirculation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.3233\/CH-131692","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.3233\/CH-131692","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T15:10:59Z","timestamp":1777389059000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.3233\/CH-131692"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,1]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,8]]}},"alternative-id":["10.3233\/CH-131692"],"URL":"https:\/\/doi.org\/10.3233\/ch-131692","relation":{},"ISSN":["1386-0291","1875-8622"],"issn-type":[{"value":"1386-0291","type":"print"},{"value":"1875-8622","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,1]]}}}