{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T16:27:14Z","timestamp":1791044834375,"version":"4.1.0"},"reference-count":38,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2020,9,25]],"date-time":"2020-09-25T00:00:00Z","timestamp":1600992000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clinical Hemorheology and Microcirculation"],"published-print":{"date-parts":[[2020,9,25]]},"abstract":"<jats:sec specific-use=\"heading-level-1\">\n                    <jats:title>PURPOSE:<\/jats:title>\n                    <jats:p>Contrast-enhanced-ultrasound (CEUS) has been frequently used in assessment of cystic renal lesions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec specific-use=\"heading-level-1\">\n                    <jats:title>OBJECTIVE:<\/jats:title>\n                    <jats:p>The aim of this study was to investigate the Bosniak classification in CEUS compared to CT and MRI in a multi-center setting.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec specific-use=\"heading-level-1\">\n                    <jats:title>METHODS:<\/jats:title>\n                    <jats:p>Bosniak classification in CEUS examinations of cystic renal lesions were compared to imaging findings in computed-tomography (ceCT) and magnetic-resonance-imaging (ceMRI). Imaging results were correlated to histopathological reports. All examinations were performed by experts (EFSUMB level 3) using up-to-date CEUS examination-protocols.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec specific-use=\"heading-level-1\">\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>\n                      Overall, 173 cystic renal lesions were compared to subgroups CT (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      \u200a=\u200a87) and MRI (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      \u200a=\u200a86). Using Bosniak-classification 64\/87 renal cysts (73.6%) were rated equal compared to CT with upgrade of four lesions (4.6%) and downgrade of 19 lesions (21.8%) by CT (Intra-class-correlation [ICC] coefficient of 0.824 [\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u200a&lt;\u200a0.001]). CEUS compared to MRI, presenting different scoring especially in classes Bosniak IIF (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      \u200a=\u200a16\/31) and Bosniak III (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      \u200a=\u200a16\/28) with an ICC coefficient of 0.651 (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u200a&lt;\u200a0.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec specific-use=\"heading-level-1\">\n                    <jats:title>CONCLUSION:<\/jats:title>\n                    <jats:p>CEUS can visualize even finest septal and small nodular wall enhancement, which may result in an upgrade of cystic lesions into a higher Bosniak class compared to CT or MRI. Thus, a modification of the Bosniak classification on CEUS may reduce unnecessary biopsies and surgery.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3233\/ch-190764","type":"journal-article","created":{"date-parts":[[2020,2,7]],"date-time":"2020-02-07T14:41:01Z","timestamp":1581086461000},"page":"419-429","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":30,"title":["Contrast-enhanced ultrasound (CEUS) of cystic renal lesions in comparison to CT and MRI in a multicenter setting"],"prefix":"10.1177","volume":"75","author":[{"given":"Markus Herbert","family":"Lerchbaumer","sequence":"first","affiliation":[{"name":"Universit\u00e4tzu Berlin","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franz Josef","family":"Putz","sequence":"additional","affiliation":[{"name":"University Hospital Regensburg","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes","family":"R\u00fcbenthaler","sequence":"additional","affiliation":[{"name":"Ludwig-Maximilians-University of Munich","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julian","family":"Rogasch","sequence":"additional","affiliation":[{"name":"Universit\u00e4tzu Berlin","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ernst-Michael","family":"Jung","sequence":"additional","affiliation":[{"name":"University Medical Center Regensburg","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dirk-Andre","family":"Clevert","sequence":"additional","affiliation":[{"name":"Ludwig-Maximilians-University of Munich","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernd","family":"Hamm","sequence":"additional","affiliation":[{"name":"Universit\u00e4tzu Berlin","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcus","family":"Makowski","sequence":"additional","affiliation":[{"name":"Universit\u00e4tzu Berlin","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Fischer","sequence":"additional","affiliation":[{"name":"Universit\u00e4tzu Berlin","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,12,19]]},"reference":[{"issue":"10","key":"e_1_3_2_2_2","first-page":"555","article-title":"Simple renal cyst: An observation","volume":"95","author":"Pal DK","year":"1997","unstructured":"PalDK, KunduAK, DasS. 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