{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T21:04:27Z","timestamp":1777496667240,"version":"3.51.4"},"reference-count":48,"publisher":"SAGE Publications","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["CH"],"published-print":{"date-parts":[[2020,12,22]]},"abstract":"<jats:p>The most important and consulted guidelines dealing with not healing foot ulcers suggest the measurement of the foot perfusion (FP) to exclude the critical limb ischemia (CLI), because of the high risk of limb amputation. But the recommended cut-off values of FP fail to include all the heterogeneity of patients of the real-life with a not healing ulcer. Often these patients are diabetics with a moderate PAD but with a high level of infection. To meet this goal, in 2014, the Society for Vascular Surgery has published the \u201cLower Extremity Threatened Limb Classification System: Risk stratification based on Wound, Infection, and foot Ischemia (WIfI).\u201d This new classification system has changed the criteria of assessment of limb amputation risk, replacing the single cut-off value role with a combination of a spectrum of perfusion values along with graded infection and dimension levels of skin ulcers. The impact of this new classification system was remarkable so to propose the substitution of the CLI definition, with the new Critical limb-threatening ischemia (CLTI), that seems to define the limb amputation risk more realistically<\/jats:p>","DOI":"10.3233\/ch-200901","type":"journal-article","created":{"date-parts":[[2020,7,16]],"date-time":"2020-07-16T11:37:15Z","timestamp":1594899435000},"page":"405-412","source":"Crossref","is-referenced-by-count":4,"title":["Current opinion on the role of the foot perfusion in limb amputation risk assessment"],"prefix":"10.1177","volume":"76","author":[{"given":"Romeo","family":"Martini","sequence":"first","affiliation":[{"name":"Unit\u00e0 Operativa di Angiologia, Azienda Ospedaliera Universitaria di Padova, Padova, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","reference":[{"issue":"2 Suppl","key":"10.3233\/CH-200901_ref1","doi-asserted-by":"publisher","first-page":"3S","DOI":"10.1016\/j.jvs.2014.04.049","article-title":"Management of venous leg ulcers: clinical practice guidelines of the Society for Vascular Surgery and the American Venous Forum","volume":"60","author":"O\u2019Donnell","year":"2014","journal-title":"J Vasc Surg"},{"issue":"1","key":"10.3233\/CH-200901_ref2","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1111\/wrr.12391","article-title":"WHS guidelines update: Diabetic foot ulcer treatment guidelines. 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