{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T01:02:14Z","timestamp":1777510934418,"version":"3.51.4"},"reference-count":0,"publisher":"SAGE Publications","issue":"1-3","license":[{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clinical Hemorheology and Microcirculation"],"published-print":{"date-parts":[[2011,6]]},"abstract":"<jats:p>Purpose: The objective was to characterize the microcirculation of parathyroid adenomas using contrast-enhanced ultrasound (CEUS) and to evaluate if it can be used for diagnosis and localization of pathologic glands. Patients and methods: Thirty patients with primary hyperparathyroidism scheduled for parathyroidectomy were enrolled. Preoperatively, all patients underwent B-Scan sonography, Colour coded Doppler Sonography (CCDS), Power Doppler (PD) and CEUS. The diagnostic confidence concerning B-Scan, CCDS, PD and CEUS was classified into six grades (0: no adenoma; 5: adenoma). Results: Using CEUS, all adenomatous glands showed a typical dynamic microvascularization. B-Scan showed a mean grade of 2.18, CCDS 2.29, PD 2.33, CEUS 4.29 (6\u20139 MHz transducer) and 3.52 (6\u201315 MHz). The differences between CEUS and conventional sonography were all statistically significant (p &lt; 0.05). CEUS noted a sensitivity of 98.4% and specificity of 98.4% for the detection of adenomatous glands. Conclusion: CEUS facilitates the detection and diagnosis of pathologic parathyroid glands due to their typical microvascularization.<\/jats:p>","DOI":"10.3233\/ch-2011-1402","type":"journal-article","created":{"date-parts":[[2019,12,2]],"date-time":"2019-12-02T13:06:21Z","timestamp":1575291981000},"page":"95-103","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":18,"title":["Evaluation of the microvascularization of pathologic parathyroid glands in patients with primary hyperparathyroidism using conventional ultrasound and contrast-enhanced ultrasound"],"prefix":"10.1177","volume":"48","author":[{"given":"W.","family":"Uller","sequence":"first","affiliation":[{"name":"Department of Radiology, University Medical Center of Regensburg, Regensburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.M.","family":"Jung","sequence":"additional","affiliation":[{"name":"Department of Radiology, University Medical Center of Regensburg, Regensburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Hornung","sequence":"additional","affiliation":[{"name":"Department of Surgery, University Medical Center of Regensburg, Regensburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Ross","sequence":"additional","affiliation":[{"name":"Department of Radiology, University Medical Center of Regensburg, Regensburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.","family":"Jung","sequence":"additional","affiliation":[{"name":"University of Saarbr\u00fccken, Saarbr\u00fccken, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.J.","family":"Schlitt","sequence":"additional","affiliation":[{"name":"Department of Surgery, University Medical Center of Regensburg, Regensburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Stroszczynski","sequence":"additional","affiliation":[{"name":"Department of Radiology, University Medical Center of Regensburg, Regensburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Agha","sequence":"additional","affiliation":[{"name":"Department of Surgery, University Medical Center of Regensburg, Regensburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2011,1]]},"container-title":["Clinical Hemorheology and Microcirculation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.3233\/CH-2011-1402","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.3233\/CH-2011-1402","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T15:09:30Z","timestamp":1777388970000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.3233\/CH-2011-1402"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,1]]},"references-count":0,"journal-issue":{"issue":"1-3","published-print":{"date-parts":[[2011,6]]}},"alternative-id":["10.3233\/CH-2011-1402"],"URL":"https:\/\/doi.org\/10.3233\/ch-2011-1402","relation":{},"ISSN":["1386-0291","1875-8622"],"issn-type":[{"value":"1386-0291","type":"print"},{"value":"1875-8622","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,1]]}}}