{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T12:12:33Z","timestamp":1790338353631,"version":"4.1.0"},"reference-count":0,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clinical Hemorheology and Microcirculation"],"published-print":{"date-parts":[[2012,8]]},"abstract":"<jats:p>\n                    This study tested the hypothesis that trained sickle cell trait (SCT) carriers are not subjected to greater risk of rhabdomyolysis or renal failure in response to moderate submaximal exercise than subjects with normal hemoglobin (CONT). Blood markers in 11 trained SCT carriers and 12 control counterparts were measured before and after 40 min of exercise at 55% of peak power output (Ppeak) conducted in thermoneutral environment. Body weights decreased with exercise in the same proportion in the two groups (from 65.1 \u00b1 7.0 kg to 64.1 \u00b1 7.0 kg and from 70.2 \u00b1 6.6 to 68.6 \u00b1 6.6 kg at the end of exercise in SCT and CONT, respectively). Heart rate and rectal temperature increased in the two groups in response to exercise, but the groups remained closely matched. Serum urea, CRP, CK and LDH were similar in the two groups and remained unchanged in response to exercise. Creatinine, Na\n                    <jats:sup>+<\/jats:sup>\n                    , K\n                    <jats:sup>+<\/jats:sup>\n                    , Cl\n                    <jats:sup>\u2212<\/jats:sup>\n                    and myoglobin concentrations increased above baseline in response to exercise, with changes of the same magnitude in the two groups. In summary, the results of the present study suggest that moderate submaximal exercise is not unsafe from a biochemical point of view for sportsmen carrying SCT.\n                  <\/jats:p>","DOI":"10.3233\/ch-2011-1524","type":"journal-article","created":{"date-parts":[[2019,12,2]],"date-time":"2019-12-02T13:09:33Z","timestamp":1575292173000},"page":"193-202","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Moderate endurance exercise is not a risk for rhabdomyolysis or renal failure in sickle cell trait carriers"],"prefix":"10.1177","volume":"51","author":[{"given":"Laurent","family":"Messonnier","sequence":"first","affiliation":[{"name":"Laboratory of Exercise Physiology, University of Savoie, Chambery, and University Jean Monnet of Saint-Etienne, Saint-Etienne, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdoulaye","family":"Samb","sequence":"additional","affiliation":[{"name":"Laboratory of Physiology, Faculty of Medicine and Pharmacy, University Cheikh Anta Diop, Dakar, Senegal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julien","family":"Tripette","sequence":"additional","affiliation":[{"name":"Laboratory ACTES, Department of Physiology, University of The French West Indies, Pointe-a-Pitre, Guadeloupe"},{"name":"UMR Inserm, University of The French West Indies, Pointe-a-Pitre, Guadeloupe"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bertin Doubi","family":"Gogh","sequence":"additional","affiliation":[{"name":"Laboratory of Physiology and Functional Experiment, Research Medical School, University of Cocody, Abidjan, Cote d'Ivoire"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gylna","family":"Loko","sequence":"additional","affiliation":[{"name":"Laboratory ACTES, Department of Physiology, University of The French West Indies, Pointe-a-Pitre, Guadeloupe"},{"name":"Sickle Cell Center, Medical Center of Lamentin, Martinique"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Niama Diop","family":"Sall","sequence":"additional","affiliation":[{"name":"Laboratory of Physiology, Faculty of Medicine and Pharmacy, University Cheikh Anta Diop, Dakar, Senegal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L\u00e9onard","family":"F\u00e9asson","sequence":"additional","affiliation":[{"name":"Laboratory of Exercise Physiology, University of Savoie, Chambery, and University Jean Monnet of Saint-Etienne, Saint-Etienne, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivier","family":"Hue","sequence":"additional","affiliation":[{"name":"Laboratory ACTES, Department of Physiology, University of The French West Indies, Pointe-a-Pitre, Guadeloupe"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandrine","family":"Lamothe","sequence":"additional","affiliation":[{"name":"Sickle Cell Center, Academic Medical Center, Pointe-a-Pitre, Guadeloupe"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pascal","family":"Bogui","sequence":"additional","affiliation":[{"name":"Laboratory of Physiology and Functional Experiment, Research Medical School, University of Cocody, Abidjan, Cote d'Ivoire"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Connes","sequence":"additional","affiliation":[{"name":"Laboratory ACTES, Department of Physiology, University of The French West Indies, Pointe-a-Pitre, Guadeloupe"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2012,1,1]]},"container-title":["Clinical Hemorheology and Microcirculation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.3233\/CH-2011-1524","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.3233\/CH-2011-1524","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T15:10:29Z","timestamp":1777389029000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.3233\/CH-2011-1524"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,1,1]]},"references-count":0,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2012,8]]}},"alternative-id":["10.3233\/CH-2011-1524"],"URL":"https:\/\/doi.org\/10.3233\/ch-2011-1524","relation":{"is-cited-by":[{"id-type":"doi","id":"10.1155\/2017\/7191826","asserted-by":"object"}]},"ISSN":["1386-0291","1875-8622"],"issn-type":[{"value":"1386-0291","type":"print"},{"value":"1875-8622","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,1,1]]}}}