{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T21:04:31Z","timestamp":1777496671983,"version":"3.51.4"},"reference-count":31,"publisher":"SAGE Publications","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["CH"],"published-print":{"date-parts":[[2020,10,30]]},"abstract":"<jats:p>BACKGRUND: The coagulation status of burn patients is generally impaired and is a major factor of the deteriorating burn patients\u2019 overall situation. In trauma and other patient groups, the differential diagnosis of coagulation impairment has been largely improved by the use of rotational thromboelastometry (ROTEM\u00ae). The aim of this prospective observational study was the differentiated observation of coagulopathy in severely burned patients using standard parameters and ROTEM\u00ae thrombelastometry during the relevant stages of burn disease. PATIENTS AND METHODS: Twelve patients that sustained at least 20% third degree burns of total body surface area (TBSA) were included in the study. Standard and ROTEM\u00ae coagulation analyses were performed on admission and then twice daily during the first 14 days following burn trauma. RESULTS: Although the initial assessment of DIC was similar for both standard labs and ROTEM\u00ae measurements, more patients were detected to be in a state of worsening coagulation status for a longer time in ROTEM\u00ae than in standard measurements. In addition, one patient was rated in to be in decompensated DIC for 3 days according to ROTEM\u00ae measurements, while no patient was rated to be in a decompensated DIC based on standard parameters. CONCLUSION: This study points towards a more complex picture and higher occurrence of DIC in burn patients when thrombelastometric measurements like ROTEM\u00ae are taken into account in addition to standard coagulation parameters.<\/jats:p>","DOI":"10.3233\/ch-209210","type":"journal-article","created":{"date-parts":[[2020,9,8]],"date-time":"2020-09-08T09:59:21Z","timestamp":1599559161000},"page":"299-308","source":"Crossref","is-referenced-by-count":3,"title":["Is major burn injury associated with coagulopathy? The value of thrombelastometry in the detection of coagulopathy in major burn injury: A prospective observational study"],"prefix":"10.1177","volume":"76","author":[{"given":"Daniel","family":"Lonic","sequence":"first","affiliation":[{"name":"Department of Plastic, Hand, and Reconstructive Surgery, University Medical Center Regensburg, Germany"},{"name":"Department of Plastic, Reconstructive and Aesthetic Surgery, Helios Hospital Munich West, Munich, Germany"},{"name":"Department of Plastic, Reconstructive, Hand and Burn Surgery, Bogenhausen Academic Teaching Hospital, Munich, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul I.","family":"Heidekrueger","sequence":"additional","affiliation":[{"name":"Department of Plastic, Hand, and Reconstructive Surgery, University Medical Center Regensburg, Germany"},{"name":"Department of Plastic, Reconstructive, Hand and Burn Surgery, Bogenhausen Academic Teaching Hospital, Munich, 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