{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T21:16:03Z","timestamp":1777497363242,"version":"3.51.4"},"reference-count":37,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2023,1,20]],"date-time":"2023-01-20T00:00:00Z","timestamp":1674172800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clinical Hemorheology and Microcirculation"],"published-print":{"date-parts":[[2023,7,18]]},"abstract":"<jats:sec specific-use=\"heading-level-1\">\n                    <jats:title>BACKGROUND:<\/jats:title>\n                    <jats:p>Complete atrioventricular block is most commonly caused by age-related degeneration and fibrosis in the cardiac conduction system and is called primary idiopathic complete atrioventricular (iCAVB). Although many factors affect this situation, which increases with age in the cardiac conduction system, the relationship between whole blood viscosity (WBV) and iCAVB has not been clarified until now. In this study, we aim to reveal the relationship between iCAVB and WBV.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec specific-use=\"heading-level-1\">\n                    <jats:title>METHODS AND RESULTS:<\/jats:title>\n                    <jats:p>\n                      141 patients with dual-chamber permanent pacemaker implanted for iCAVB and 140 age- and sex-matched subjects were included in this study. The WBV values of the study groups were compared in both high shear rate (HSR) and low shear rate (LSR). Both WBV at HSR and WBV at LSR were significantly higher in the iCAVB group compared to the control group (16.11 [15.14\u201316.89] vs 14.40 [13.62\u201315.58]; 39.82 [17.43\u201355.23] vs 1.38 [\u201313.14\u201326.73];\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u200a&lt;\u200a0.001, respectively). The patient population was followed up for an median of 38 months for all-cause mortality. Higher mortality rates were found in higher WBV at HSR and WBV at LSR (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u200a&lt;\u200a0.001,for both).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec specific-use=\"heading-level-1\">\n                    <jats:title>CONCLUSIONS:<\/jats:title>\n                    <jats:p>In this study, WBV was found to be an independent predictor for iCAVB, and in these patients WBV was associated with poor clinical outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3233\/ch-221596","type":"journal-article","created":{"date-parts":[[2023,1,20]],"date-time":"2023-01-20T10:48:12Z","timestamp":1674211692000},"page":"141-151","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Increased whole blood viscosity is associated with primary idiopathic complete atrioventricular block and poor clinical outcomes in these patients"],"prefix":"10.1177","volume":"84","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8923-8709","authenticated-orcid":false,"given":"Kenan","family":"Toprak","sequence":"first","affiliation":[{"name":"Harran University","place":["Turkey"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mustafa","family":"Kaplangoray","sequence":"additional","affiliation":[{"name":"Mehmet Akif \u0130nan Training and Research Hospital","place":["Turkey"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali","family":"Palice","sequence":"additional","affiliation":[{"name":"Mehmet Akif \u0130nan Training and Research Hospital","place":["Turkey"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehmet","family":"\u0130nan\u0131r","sequence":"additional","affiliation":[{"name":"Abant Izzet Baysal University","place":["Turkey"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tolga","family":"Memio\u011flu","sequence":"additional","affiliation":[{"name":"Abant Izzet Baysal University","place":["Turkey"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zafer","family":"K\u00f6k","sequence":"additional","affiliation":[{"name":"Izzet Baysal Training and Research Hospital","place":["Turkey"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u0130brahim Halil","family":"Alt\u0131parmak","sequence":"additional","affiliation":[{"name":"Harran University","place":["Turkey"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u0130brahim Halil","family":"Toprak","sequence":"additional","affiliation":[{"name":"Harran University","place":["Turkey"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Asuman","family":"Bi\u00e7er","sequence":"additional","affiliation":[{"name":"Harran University","place":["Turkey"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Recep","family":"Demirba\u011f","sequence":"additional","affiliation":[{"name":"Harran University","place":["Turkey"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2023,1,20]]},"reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.111.246876"},{"issue":"1","key":"e_1_3_1_3_2","first-page":"32","article-title":"Modificazionidell\u2019elettrocardiogramma nell\u2019anziano","volume":"86","author":"Molaschi M","year":"1995","unstructured":"MolaschiM, PonzettoM, RominR, BerrinoE and FabrisF. Modificazionidell\u2019elettrocardiogramma nell\u2019anziano. Limiti tra normalit\u00e0 epatologia [Changes in the electrocardiogram in the elderly patient. The limits between normality and pathology]. Recenti Prog Med. 1995;86(1):32\u20136.","journal-title":"Limiti tra normalit\u00e0 epatologia [Changes in the electrocardiogram in the elderly patient. The limits between normality and pathology]. Recenti Prog Med"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1975.00330030055006"},{"key":"e_1_3_1_5_2","doi-asserted-by":"crossref","unstructured":"ZiadIF MillerJM and ZipesDP. Atrioventricular conduction abnormalities. Clinical arrhythmology and electrophysiology; a companion to Braunwald\u2019s heart disease. 2nd edition. 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