{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T09:14:05Z","timestamp":1777540445436,"version":"3.51.4"},"reference-count":16,"publisher":"SAGE Publications","issue":"1-2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["CH"],"published-print":{"date-parts":[[2024,2,22]]},"abstract":"<jats:p>BACKGROUND: The use of dyes like Indocyanine green (ICG) and Patent blue facilitates the identification of lymphatic vessels during lymphaticovenous anastomosis (LVA) surgery. However, some patients experience \u201cstaining failure\u201d. In these cases, no stained lymphatic vessels can be detected, making supermicrosurgical LVA even more complex. OBJECTIVE: This study aims to investigate patient-related factors that may interfere with lymphatic vessel staining during LVA. METHODS: A retrospective study was conducted on 30 patient charts, focusing on patient characteristics and the staining quality of ICG and Patent blue dye. Statistical analyses were performed to identify correlations between variables. RESULTS: Significant correlations were found between higher age and secondary lymphedema, longer duration of lymphedema in male patients until surgery and reoccurring cellulitis and Patent blue staining. Notably, recurrent infections to the lymphatic system resulted in inferior staining ability during LVA surgery. CONCLUSIONS: Due to staining failure the detection of functional lymphatic vessels remains challenging in LVA surgery. A more extensive preoperative workup is recommended for patients with recurrent cellulitis to optimize surgical feasibility and procedure quality in LVA treatment for lymphedema.<\/jats:p>","DOI":"10.3233\/ch-238112","type":"journal-article","created":{"date-parts":[[2023,9,12]],"date-time":"2023-09-12T13:36:54Z","timestamp":1694525814000},"page":"153-158","source":"Crossref","is-referenced-by-count":1,"title":["Patient characteristics may affect the lymphatic staining ability of Indocyanine green and Patent blue during lymphaticovenous anastomosis"],"prefix":"10.1177","volume":"86","author":[{"given":"Niklas","family":"Biermann","sequence":"first","affiliation":[{"name":"Department of Plastic, Hand and Reconstructive Surgery, University Hospital Regensburg, Regensburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisabeth","family":"Eschenbacher","sequence":"additional","affiliation":[{"name":"Department of Plastic, Hand and Reconstructive Surgery, 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