{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T16:26:59Z","timestamp":1777393619108,"version":"3.51.4"},"reference-count":0,"publisher":"SAGE Publications","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAD"],"published-print":{"date-parts":[[2014,12,2]]},"DOI":"10.3233\/jad-140783","type":"journal-article","created":{"date-parts":[[2018,6,4]],"date-time":"2018-06-04T13:37:45Z","timestamp":1528119465000},"page":"871-891","source":"Crossref","is-referenced-by-count":34,"title":["Serum MHPG Strongly Predicts Conversion to Alzheimer's Disease in Behaviorally Characterized Subjects with Down Syndrome"],"prefix":"10.1177","volume":"43","author":[{"given":"Alain D.","family":"Dekker","sequence":"first","affiliation":[{"name":"Department of Neurology and Alzheimer Research Center, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands"},{"name":"Laboratory of Neurochemistry and Behaviour, Institute Born-Bunge, University of Antwerp, Wilrijk, Antwerp, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonia M.W.","family":"Coppus","sequence":"additional","affiliation":[{"name":"Dichterbij, Center for the Intellectually Disabled, Gennep, The Netherlands"},{"name":"Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands"},{"name":"Department of Primary and Community Care, Radboud University Medical Center, Nijmegen, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yannick","family":"Vermeiren","sequence":"additional","affiliation":[{"name":"Laboratory of Neurochemistry and Behaviour, Institute Born-Bunge, University of Antwerp, Wilrijk, Antwerp, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tony","family":"Aerts","sequence":"additional","affiliation":[{"name":"Laboratory of Neurochemistry and Behaviour, Institute Born-Bunge, University of Antwerp, Wilrijk, Antwerp, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cornelia M.","family":"van Duijn","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Berry P.","family":"Kremer","sequence":"additional","affiliation":[{"name":"Department of Neurology and Alzheimer Research Center, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pieter J.W.","family":"Naud\u00e9","sequence":"additional","affiliation":[{"name":"Department of Neurology and Alzheimer Research Center, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Debby","family":"Van Dam","sequence":"additional","affiliation":[{"name":"Laboratory of Neurochemistry and Behaviour, Institute Born-Bunge, University of Antwerp, Wilrijk, Antwerp, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter P.","family":"De Deyn","sequence":"additional","affiliation":[{"name":"Department of Neurology and Alzheimer Research Center, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands"},{"name":"Laboratory of Neurochemistry and Behaviour, Institute Born-Bunge, University of Antwerp, Wilrijk, Antwerp, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","container-title":["Journal of Alzheimer's Disease"],"original-title":[],"link":[{"URL":"https:\/\/content.iospress.com\/download?id=10.3233\/JAD-140783","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T10:01:14Z","timestamp":1777370474000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.3233\/JAD-140783"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,12,2]]},"references-count":0,"journal-issue":{"issue":"3"},"URL":"https:\/\/doi.org\/10.3233\/jad-140783","relation":{"is-cited-by":[{"id-type":"doi","id":"10.3389\/fnbeh.2016.00120","asserted-by":"object"}]},"ISSN":["1875-8908","1387-2877"],"issn-type":[{"value":"1875-8908","type":"electronic"},{"value":"1387-2877","type":"print"}],"subject":[],"published":{"date-parts":[[2014,12,2]]}}}