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The aim of this work was to compare the validity and reliability of these cognitive tests in a primary care based cohort (pcb-Cohort). The MMSE and the CDR were applied to 568 volunteers in the pcb-Cohort. Distinct cut-off points for the MMSE were considered, namely MMSE 27, MMSE 24, and MMSE PT (adapted for the Portuguese population). The MMSE 27 identified the greatest number of putative dementia cases, and, as determined by the ROC curve, it was the most sensitive and specific of the MMSE cut-offs considered. Putative predictive or risk factors identified included age, literacy, depression, and diabetes mellitus (DM). DM has previously been indicated as a risk factor for dementia and Alzheimer\u2019s disease. Comparatively, the MMSE 27 cut-off has the greatest sensibility (94.9%) and specificity (66.3%) when compared to MMSE PT and MMSE 24. Upon comparing MMSE and CDR scores, the latter identified a further 146 putative dementia cases, thus permitting one to propose that in an ideal situation, both tests should be employed. This increases the likelihood of identifying putative dementia cases for subsequent follow up work, thus these cognitive tests represent important tools in patient care. Further, this is a significant study for Portuguese populations, where few of these studies have been carried out.<\/jats:p>","DOI":"10.3233\/jad-170501","type":"journal-article","created":{"date-parts":[[2017,11,10]],"date-time":"2017-11-10T10:22:51Z","timestamp":1510309371000},"page":"157-167","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":13,"title":["Putative Dementia Cases Fluctuate as a Function of Mini-Mental State Examination Cut-Off Points"],"prefix":"10.1177","volume":"61","author":[{"given":"Ilka M.","family":"Rosa","sequence":"first","affiliation":[{"name":"University of Aveiro","place":["Portugal"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana G.","family":"Henriques","sequence":"additional","affiliation":[{"name":"University of Aveiro","place":["Portugal"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jens","family":"Wiltfang","sequence":"additional","affiliation":[{"name":"University of Aveiro","place":["Portugal"]},{"name":"University Medicine G\u00f6ttingen","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Odete A.B.","family":"da Cruz e Silva","sequence":"additional","affiliation":[{"name":"University of Aveiro","place":["Portugal"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2017,11,8]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/srep30319"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.43.11.2412-a"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2003-38269"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.57.5.643"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0404.2002.01225.x"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1159\/000092808"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.3233\/JAD-2009-0994"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/gps.2334"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13195-016-0176-z"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.3233\/JAD-141626"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3956(75)90026-6"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.JGP.0000192478.82189.a8"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00391-013-0488-6"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.dadm.2014.11.007"},{"key":"e_1_3_3_16_2","first-page":"343","article-title":"The validity of using the Mini Mental State Examination in NICE dementia guidelines","volume":"75","author":"Davey RJ","year":"2004","unstructured":"DaveyRJ, JamiesonS (2004) The validity of using the Mini Mental State Examination in NICE dementia guidelines. 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