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These comorbidities may help explain the overlapping neuropsychiatric symptoms between AD and other dementias. Data on 221 AD patients with Neuropsychiatric Inventory-Questionnaire were obtained from the National Alzheimer\u2019s Coordinating Center. TDP-43 was associated with aberrant motor activity, whereas Lewy bodies were associated with anxiety, irritability, sleep behavior, and appetite problems. The associations between these comorbidities and neuropsychiatric symptoms were more significant for patients with sparse diffuse plaques.<\/jats:p>","DOI":"10.3233\/jad-181285","type":"journal-article","created":{"date-parts":[[2019,5,21]],"date-time":"2019-05-21T16:25:49Z","timestamp":1558455949000},"page":"953-961","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":48,"title":["Associations between Comorbid TDP-43, Lewy Body Pathology, and Neuropsychiatric Symptoms in Alzheimer\u2019s Disease"],"prefix":"10.1177","volume":"69","author":[{"given":"Ece","family":"Bayram","sequence":"first","affiliation":[{"name":"Cleveland Clinic Lou Ruvo Center for Brain Health, Las Vegas, NV, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guogen","family":"Shan","sequence":"additional","affiliation":[{"name":"Department of Environmental and Occupational Health, Epidemiology and Biostatistics Program, University 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