{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T17:07:05Z","timestamp":1777396025108,"version":"3.51.4"},"reference-count":22,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2019,12,23]],"date-time":"2019-12-23T00:00:00Z","timestamp":1577059200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Alzheimer\u2019s Disease"],"published-print":{"date-parts":[[2020,1,21]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Semantic intrusion errors on memory tests may represent very early cognitive changes associated with elevated Alzheimer\u2019s disease pathology within the brain, including amyloid-\u03b2 (A\u03b2). Subscales that measure proactive semantic interference (PSI) and intrusions related to PSI on the Loewenstein Acevedo Scales of Semantic Interference and Learning (LASSI-L) have been associated with high levels of brain amyloid load, structural changes on brain MRI in Hispanic and non-Hispanic groups. It is presently unknown whether intrusion errors or other measures of the LASSI-L can differentiate between African-American (AA) older adults diagnosed with amnestic mild cognitive impairment (aMCI) or classified as cognitively normal (CN).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>This study examined the extent to which a high percentage of semantic intrusion errors on LASSI-L subscales susceptible to PSI and other LASSI-L measures could differentiate between AA aMCI and CN groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Forty-eight AA older adults were recruited (27 CN and 21 aMCI) and received a through clinical and neuropsychological evaluation. The LASSI-L was administered independent of diagnostic classification.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>With and without statistical adjustment for literacy, AA aMCI participants scored lower on all LASSI-L measures. ROC analyses revealed an area under the curve exceeding 90% and correctly classified 86% of AA aMCI with 82% specificity for AA CN participants.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Percentage of intrusion errors on the LASSI-L subscales susceptible to PSI differentiated AA aMCI from AA CN. This adds to emerging evidence indicating that the LASSI-L may be culturally appropriate and can differentiate between aMCI and CN in diverse ethnic\/cultural groups.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3233\/jad-191022","type":"journal-article","created":{"date-parts":[[2019,12,24]],"date-time":"2019-12-24T07:57:43Z","timestamp":1577174263000},"page":"785-790","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":12,"title":["Semantic Intrusion Error Ratio Distinguishes Between Cognitively Impaired and Cognitively Intact African American Older Adults"],"prefix":"10.1177","volume":"73","author":[{"given":"Kimberly E.","family":"Capp","sequence":"first","affiliation":[{"name":"Nova Southeastern University, Davie, FL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosie E.","family":"Curiel Cid","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Behavioral Sciences, Center for Cognitive Neuroscience and Aging, University of Miami Miller School of Medicine, Miami, FL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth A.","family":"Crocco","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Behavioral Sciences, Center for Cognitive Neuroscience and Aging, University of Miami Miller School of Medicine, Miami, FL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashley","family":"Stripling","sequence":"additional","affiliation":[{"name":"Nova Southeastern University, Davie, FL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcela","family":"Kitaigorodsky","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Behavioral Sciences, Center for Cognitive Neuroscience and Aging, University of Miami Miller School of Medicine, Miami, FL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis A.","family":"Sierra","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Behavioral Sciences, Center for Cognitive Neuroscience and Aging, University of Miami Miller School of Medicine, Miami, FL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose G.","family":"Melo","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Behavioral Sciences, Center for Cognitive Neuroscience and Aging, University of Miami Miller School of Medicine, Miami, FL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David A.","family":"Loewenstein","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Behavioral Sciences, Center for Cognitive Neuroscience and Aging, University of Miami Miller School of Medicine, Miami, FL, 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