{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T16:48:51Z","timestamp":1777394931226,"version":"3.51.4"},"reference-count":31,"publisher":"SAGE Publications","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAD"],"published-print":{"date-parts":[[2021,1,5]]},"abstract":"<jats:p>Background: The outbreak of the COVID-19 pandemic seems to have mental health implications for both people with neurocognitive disorder and their caregivers. Objective: The study aimed to shed light on relations between caregiver mental reaction to the pandemic and caregiver distress related to neuropsychiatric symptoms, memory impairment progression, and functional impairment of people with neurocognitive disorder during the period of confinement in Greece. Methods: The study included caregivers of patients with mild (N\u200a=\u200a13) and major (N\u200a=\u200a54) neurocognitive disorder. The caregiver-based telephone interview was based on items of the neuropsychiatric inventory questionnaire, the AD8 Dementia Screening Instrument, and the Bristol Activities of Daily Living Scale. Regarding the mental impact of the COVID-19 crisis on caregivers, four single questions referring to their worries in the last seven days were posed, in addition to the scales Generalized Anxiety Disorder 7-Item (GAD-7) and the 22-item Impact of Event Scale-revised (IES-R). A stepwise linear regression model was employed for studying the relationship between caregiver distress and demographic and clinical data and caregiver mental reaction to COVID-19 pandemic outbreak. Results: Caregiver distress severity during the confinement period was influenced not only by memory deficits (p\u200a=\u200a0.009) and neuropsychiatric symptoms (p\u200a&lt;\u200a0.001) of patients, but also by caregiver hyperarousal (p\u200a=\u200a0.003) and avoidance symptoms (p\u200a=\u200a0.033) and worries directly linked to the COVID-19 crisis (p\u200a=\u200a0.022). Conclusion: These observations provide further evidence for the urgent need for support of caregivers of patients with neurocognitive disorder during the COVID-19 pandemic.<\/jats:p>","DOI":"10.3233\/jad-200991","type":"journal-article","created":{"date-parts":[[2020,11,13]],"date-time":"2020-11-13T10:23:42Z","timestamp":1605263022000},"page":"459-466","source":"Crossref","is-referenced-by-count":26,"title":["COVID-19 Crisis Effects on Caregiver Distress in Neurocognitive Disorder"],"prefix":"10.1177","volume":"79","author":[{"given":"Panagiotis","family":"Alexopoulos","sequence":"first","affiliation":[{"name":"Department of Psychiatry, Patras University Hospital, Faculty of Medicine, School of Health Sciences, University of Patras, Patras, Greece"},{"name":"Department of Psychiatry and Psychotherapy, Klinikum rechts der Isar, Faculty of Medicine, Technische Universit\u00e4t M\u00fcnchen, Munich, Germany"},{"name":"Psychogeriatric unit for neurocognitive assessment and caregiver counselling, Patras Office of The Hellenic Red Cross, Patras, Greece"},{"name":"Patras Dementia Day Care Center, Corporation for Succor and Care of Elderly and Disabled \u2013FRODIZO, Patras, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rigas","family":"Soldatos","sequence":"additional","affiliation":[{"name":"First Department of Psychiatry, Eginition Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Evangelia","family":"Kontogianni","sequence":"additional","affiliation":[{"name":"First Department of Psychiatry, Eginition Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Frouda","sequence":"additional","affiliation":[{"name":"Patras Dementia Day Care Center, Corporation for Succor and Care of Elderly and Disabled \u2013FRODIZO, Patras, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Souzana","family":"loanna Aligianni","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Patras University Hospital, Faculty of Medicine, School of Health Sciences, University of Patras, Patras, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Skondra","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Patras University Hospital, Faculty of Medicine, School of Health Sciences, University of Patras, Patras, Greece"},{"name":"Psychogeriatric unit for neurocognitive assessment and caregiver counselling, Patras Office of The Hellenic Red Cross, Patras, Greece"},{"name":"Department of Nursing, School of Health Rehabilitation Sciences, University of Patras, Patras, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Passa","sequence":"additional","affiliation":[{"name":"First Department of 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Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anastasios","family":"Politis","sequence":"additional","affiliation":[{"name":"Charing Cross Hospital, Department of Neurosurgery, Imperial College London"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Polychronis","family":"Economou","sequence":"additional","affiliation":[{"name":"Department of Civil Engineering (Statistics), University of Patras, Patras, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Alexaki","sequence":"additional","affiliation":[{"name":"First Department of Psychiatry, Eginition Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kostas","family":"Siarkos","sequence":"additional","affiliation":[{"name":"First Department of Psychiatry, Eginition Hospital, School of Medicine, National and Kapodistrian University of Athens, 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