{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T05:27:13Z","timestamp":1790832433335,"version":"4.1.0"},"reference-count":14,"publisher":"SAGE Publications","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAD"],"published-print":{"date-parts":[[2020,11,24]]},"abstract":"<jats:p>In a woman with Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) followed for 15 years, we observed magnetic resonance imaging white matter hyperintensities that vanished in the anterior temporal poles while the brain volume decreased unexpectedly. These imaging changes were transient and detected when the patient was being treated by valproic acid for stabilizing mood disturbances. This intriguing case supports that mechanisms underlying white matter hyperintensities can vary from one brain area to another and that important modifications of water influx into the brain tissue might be involved in some imaging features of CADASIL.<\/jats:p>","DOI":"10.3233\/jad-201086","type":"journal-article","created":{"date-parts":[[2020,10,13]],"date-time":"2020-10-13T13:20:33Z","timestamp":1602595233000},"page":"907-910","source":"Crossref","is-referenced-by-count":7,"title":["Vanishing White Matter Hyperintensities in CADASIL: A Case Report with Insight into Disease Mechanisms"],"prefix":"10.1177","volume":"78","author":[{"given":"Eric","family":"Jouvent","sequence":"first","affiliation":[{"name":"Universit\u00e9 de Paris, Paris, France"},{"name":"APHP, Lariboisi\u00e8re Hospital, Department of Neurology and Referral Center for rare vascular diseases of the brain and retina (CERVCO), Paris, France"},{"name":"FHU NeuroVasc, Universit\u00e9 de Paris, Paris, 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