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Among the 16 each age-matched LBD and AD patients, the CIScore differed significantly but was not correlated with CSF biomarkers. In LBD, hippocampal atrophy significantly correlated with Clinical Dementia Rating and CSF p-tau and t-tau levels. Our results showed CIS was not related to CSF biomarkers in LBD and high CSF tau levels were related to clinical disease severity and hippocampal atrophy.<\/jats:p>","DOI":"10.3233\/jad-201145","type":"journal-article","created":{"date-parts":[[2020,12,25]],"date-time":"2020-12-25T04:23:57Z","timestamp":1608870237000},"page":"1003-1008","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Cingulate Island Sign in Single Photon Emission Computed Tomography: Clinical Biomarker Correlations in Lewy Body Disease and Alzheimer\u2019s Disease"],"prefix":"10.1177","volume":"79","author":[{"given":"Akinori","family":"Futamura","sequence":"first","affiliation":[{"name":"Division of Neurology, Department of Medicine, Showa University School of Medicine, Shinagawa-ku, Tokyo, 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