{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T11:41:50Z","timestamp":1787312510728,"version":"build-2736575974"},"reference-count":71,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2021,4,20]],"date-time":"2021-04-20T00:00:00Z","timestamp":1618876800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAD"],"published-print":{"date-parts":[[2021,4,20]]},"abstract":"<jats:p>Background: Behavioral and psychological symptoms of dementia (BPSD) are quite challenging problems during the dementia course. Special Care Units for people with dementia (PwD) and BPSD (SCU-B) are residential medical structures, where BPSD patients are temporarily admitted, in case of unmanageable behavioral disturbances at home. Objective: RECage (REspectful Caring for AGitated Elderly) aspires to assess the short and long-term effectiveness of SCU-Bs toward alleviating BPSD and improving the quality of life (QoL) of PwD and their caregivers. Methods: RECage is a three-year, prospective study enrolling 500 PwD. Particularly, 250 community-dwelling PwDs presenting with severe BPSD will be recruited by five clinical centers across Europe, endowed with a SCU-B, for a short period of time; a second similar group of 250 PwD will be followed by six other no-SCU-B centers solely via outpatient visits. RECage\u2019s endpoints include short and long-term SCU-B clinical efficacy, QoL of patients and caregivers, cost-effectiveness of the SCU-B, psychotropic drug consumption, caregivers\u2019 attitude toward dementia, and time to nursing home placement. Results: PwD admitted in SCU-Bs are expected to have diminished rates of BPSD and better QoL and their caregivers are also expected to have better QoL and improved attitude towards dementia, compared to those followed in no-SCU-Bs. Also, the cost of care and the psychotropic drug consumption are expected to be lower. Finally, PwD followed in no-SCU-Bs are expected to have earlier admission to nursing homes. Conclusion: The cohort study results will refine the SCU-B model, issuing recommendations for implementation of SCU-Bs in the countries where they are scarce or non-existent.<\/jats:p>","DOI":"10.3233\/jad-201215","type":"journal-article","created":{"date-parts":[[2021,3,12]],"date-time":"2021-03-12T10:59:36Z","timestamp":1615546776000},"page":"1613-1627","source":"Crossref","is-referenced-by-count":14,"title":["Rationale, Design, and Methodology of a Prospective Cohort Study for Coping with Behavioral and Psychological Symptoms of Dementia: The RECage Project1"],"prefix":"10.1177","volume":"80","author":[{"given":"Eleni","family":"Poptsi","sequence":"first","affiliation":[{"name":"Laboratory of Psychology, Section of Cognitive and Experimental Psychology, Faculty of Philosophy, School of Psychology, Aristotle University of Thessaloniki (AUTh), Macedonia, Hellas"},{"name":"Greek Association of Alzheimer\u2019s Disease and Related Disorders (GAADRD), Thessaloniki, Makedonia, Hellas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magda","family":"Tsolaki","sequence":"additional","affiliation":[{"name":"Greek Association of Alzheimer\u2019s Disease and Related Disorders (GAADRD), Thessaloniki, Makedonia, Hellas"},{"name":"1st Department of Neurology, School of Medicine, Aristotle University of Thessaloniki (AUTh), Macedonia, Hellas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sverre","family":"Bergh","sequence":"additional","affiliation":[{"name":"Research centre for Age-Related Functional Decline and Disease, Innlandet Hospital Trust, Ottestad, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno Mario","family":"Cesana","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences and Community Health, Unit of Medical Statistics, Biometry and Bioinformatics\u201cGiulio A. Maccacaro\u201d Faculty of Medicine and Surgery, University of Milan, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfonso","family":"Ciccone","sequence":"additional","affiliation":[{"name":"Department of Neurology with Neurosurgical Activity \u201cCarlo Poma\u201d Hospital, ASST di Mantova, Mantua, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Fabbo","sequence":"additional","affiliation":[{"name":"Direttore UOC di Geriatria-Disturbi Cognitivi e Demenze, Dipartimento Cure Primarie AUSL, Modena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni B.","family":"Frisoni","sequence":"additional","affiliation":[{"name":"Memory Clinic, University Hospitals and University of Geneva, Geneva, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lutz","family":"Fr\u00f6lich","sequence":"additional","affiliation":[{"name":"Department of Geriatric Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Lavolpe","sequence":"additional","affiliation":[{"name":"Department of Neurology and CDCD Centre Humanitas Gavazzeni, Bergamo, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna Giulia","family":"Guazzarini","sequence":"additional","affiliation":[{"name":"Institute of Gerontology and Geriatrics, Department of Medicine and Surgery, University of Perugia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacques","family":"Hugon","sequence":"additional","affiliation":[{"name":"Center of Cognitive Neurology Universit\u00e9 de Paris, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Fascendini","sequence":"additional","affiliation":[{"name":"FERB Alzheimer Centre, Gazzaniga, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlo Alberto","family":"Defanti","sequence":"additional","affiliation":[{"name":"FERB Alzheimer Centre, Gazzaniga, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","reference":[{"key":"10.3233\/JAD-201215_ref1","unstructured":"Patterson C (2018) World Alzheimer Report 2018. 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