{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T07:21:15Z","timestamp":1790666475351,"version":"4.1.0"},"reference-count":59,"publisher":"SAGE Publications","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAD"],"published-print":{"date-parts":[[2021,11,9]]},"abstract":"<jats:p>Background: People with advanced dementia often exhibit responsive behaviors such as apathy, depression, agitation, aggression, and psychosis. Non-pharmacological approaches (e.g., listening to music, watching television, doing arts and crafts) are now considered as a first-line strategy to manage responsive behaviors in clinical practice due to the potential risks associated with the antipsychotic medications. To date, no evaluations of immersive non-head mounted virtual reality (VR) experience as a non-pharmacologic approach for people with advanced dementia living in nursing homes have been reported. Objective: To evaluate the feasibility (acceptance and safety) of VR experience. Methods: A single site case series (nonrandomized and unblinded) with a convenience sample (N\u200a=\u200a24; age\u200a=\u200a85.8\u00b18.6 years; Cognitive Performance Scale score\u200a=\u200a3.4\u00b10.6) measuring depression and agitation before and after the intervention. The intervention was a 30-min long research coordinator\u2013 facilitated VR experience for two weeks (10 sessions). Results: The intervention was feasible (attrition rate\u200a=\u200a0% ; adverse events\u200a=\u200a0). A reduction in depression and in agitation was observed after the intervention. However, we suggest extreme caution in interpreting this result considering the study design and small sample size. Conclusion: This study provides the basis for conducting a randomized controlled trial to evaluate the effect of VR experience on responsive behaviors in nursing homes. Since our intervention uses a smart remote-controlled projector without a headset, infectious exposure can be avoided following the COVID-19 pandemic-induced physical distancing policy in care homes.<\/jats:p>","DOI":"10.3233\/jad-210010","type":"journal-article","created":{"date-parts":[[2021,9,28]],"date-time":"2021-09-28T17:25:26Z","timestamp":1632849926000},"page":"883-893","source":"Crossref","is-referenced-by-count":17,"title":["Virtual Reality Experience Intervention May Reduce Responsive Behaviors in Nursing Home Residents with Dementia: A Case Series"],"prefix":"10.1177","volume":"84","author":[{"given":"Munira","family":"Sultana","sequence":"first","affiliation":[{"name":"Health and Rehabilitation Sciences, Western University, London, ON, Canada"},{"name":"Gait & Brain Lab, Parkwood Institute, London, ON, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen","family":"Campbell","sequence":"additional","affiliation":[{"name":"International Skin Tear Advisory Panel, Ottawa, ON, Canada"},{"name":"Primacare Living Solutions Inc. , Toronto, ON, Canada"},{"name":"Master of Clinical Science - Advanced Health Care Practice, Western University, London, ON, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Morgan","family":"Jennings","sequence":"additional","affiliation":[{"name":"Health and Rehabilitation Sciences, Western University, London, ON, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuel","family":"Montero-Odasso","sequence":"additional","affiliation":[{"name":"Gait & Brain Lab, Parkwood Institute, London, ON, Canada"},{"name":"Department of Medicine and Department of Epidemiology & Biostatistics, Western University, London, ON, Canada"},{"name":"Geriatric Medicine, St. Joseph\u2019s Health Care, London, ON, Canada"},{"name":"Lawson Health Research Institute, London, ON, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.B.","family":"Orange","sequence":"additional","affiliation":[{"name":"Lawson Health Research Institute, London, ON, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jill","family":"Knowlton","sequence":"additional","affiliation":[{"name":"Primacare Living Solutions Inc. , Toronto, ON, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Armin","family":"St. George","sequence":"additional","affiliation":[{"name":"Crosswater Digital Media, LLC, Buffalo, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dianne","family":"Bryant","sequence":"additional","affiliation":[{"name":"Lawson Health Research Institute, London, ON, Canada"},{"name":"School of Physical Therapy and Schulich School of Medicine & Dentistry (Orthopaedic Surgery), Western University, London, ON, Canada"},{"name":"Health Research Methods, Evidence and Impact, McMaster University, Hamilton, ON, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","reference":[{"key":"10.3233\/JAD-210010_ref2","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1177\/002383099200500108","article-title":"Incontinence and troublesome behaviors predict institutionalization in dementia","volume":"5","author":"O\u2019Donnell","year":"1992","journal-title":"J Geriatr Psychiatry Neurol"},{"key":"10.3233\/JAD-210010_ref3","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1001\/jama.288.12.1475","article-title":"Prevalence of neuropsychiatric symptoms in dementia and mild cognitive impairment: Results From the Cardiovascular Health Study","volume":"288","author":"Lyketsos","year":"2002","journal-title":"JAMA"},{"key":"10.3233\/JAD-210010_ref4","doi-asserted-by":"crossref","first-page":"49","DOI":"10.31887\/DCNS.2003.5.1\/fmuellerspahn","article-title":"Behavioral disturbances in dementia","volume":"5","author":"Muller-Spahn","year":"2003","journal-title":"Dialogues Clin Neurosci"},{"key":"10.3233\/JAD-210010_ref5","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1093\/ageing\/afu062","article-title":"Current prevalence of dementia, depression and behavioural problems in the older adult care home sector: The southeast London care home survey","volume":"43","author":"Stewart","year":"2014","journal-title":"Age Ageing"},{"key":"10.3233\/JAD-210010_ref7","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1159\/000084552","article-title":"Behavioral and psychological symptoms in Alzheimer\u2019s disease: Frequency and relationship with duration and severity of the disease","volume":"19","author":"Piccininni","year":"2005","journal-title":"Dement Geriatr Cogn Disord"},{"key":"10.3233\/JAD-210010_ref8","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1016\/j.archger.2008.09.002","article-title":"Depression and apathy in dementia: Same syndrome or different constructs? 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