{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T20:31:10Z","timestamp":1783542670058,"version":"3.55.0"},"reference-count":20,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2021,11,23]],"date-time":"2021-11-23T00:00:00Z","timestamp":1637625600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAD"],"published-print":{"date-parts":[[2021,11,23]]},"abstract":"<jats:p>Background: The COVID-19 pandemic has led to high mortality rates in nursing homes (NHs) in Europe. For adequate risk management and good prognostications, it is essential to identify mortality risk factors. Objective: This study aimed to determine whether previously identified risk factors for 30-day mortality in Dutch NH residents with COVID-19 are unique to COVID-19. Methods: In this cohort study, we included 1,294 NH residents with COVID-19 (cases) and 17,999 NH residents without COVID-19 (controls, from the pre-COVID-19 period). We used descriptive statistics and Cox proportional hazard models to compare mortality rates in residents with and without COVID-19, categorized by risk factors. Results: Cases had a more than 18 times higher hazard of death within 30 days compared to controls (HR 18, 95%CI: 16\u201320). For residents with COVID-19, being male, having dementia, and having Parkinson\u2019s disease (PD) were all associated with a higher 30-day mortality (HR 1.8 versus 1.3 versus 1.7). Being male was also associated with a higher mortality (HR 1.7) in the control group, whereas having dementia and PD were not. COVID-19 symptomatology was very similar for residents with and without dementia or PD, except for delirium and malaise which was more frequent in residents with dementia. Conclusion: Dementia and PD were significant additional risk factors for mortality in Dutch NH residents with COVID-19, whereas male gender was not unique to residents with COVID-19. The frailty of PD and dementia in NH residents with COVID-19 are relevant to consider in prognostication, communication, and care planning with residents and their families.<\/jats:p>","DOI":"10.3233\/jad-210319","type":"journal-article","created":{"date-parts":[[2021,9,17]],"date-time":"2021-09-17T12:51:10Z","timestamp":1631883070000},"page":"1173-1181","source":"Crossref","is-referenced-by-count":19,"title":["Dementia and Parkinson\u2019s Disease: Risk Factors for 30-Day Mortality in Nursing Home Residents with COVID-19"],"prefix":"10.1177","volume":"84","author":[{"given":"Jeanine J.S.","family":"Rutten","sequence":"first","affiliation":[{"name":"Department of Medicine for Older People, Amsterdam Public Health Research Institute, Amsterdam University Medical Center, Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janine","family":"van Kooten","sequence":"additional","affiliation":[{"name":"Department of Medicine for Older People, Amsterdam Public Health Research Institute, Amsterdam University Medical Center, Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anouk M.","family":"van Loon","sequence":"additional","affiliation":[{"name":"Department of Medicine for Older People, Amsterdam Public Health Research Institute, Amsterdam University Medical Center, Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura W.","family":"van Buul","sequence":"additional","affiliation":[{"name":"Department of Medicine for Older People, Amsterdam Public Health Research Institute, Amsterdam University Medical Center, Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karlijn J.","family":"Joling","sequence":"additional","affiliation":[{"name":"Department of Medicine for Older People, Amsterdam Public Health Research Institute, Amsterdam University Medical Center, Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Smalbrugge","sequence":"additional","affiliation":[{"name":"Department of Medicine for Older People, Amsterdam Public Health Research Institute, Amsterdam University Medical Center, Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cees M.P.M.","family":"Hertogh","sequence":"additional","affiliation":[{"name":"Department of Medicine for Older People, Amsterdam Public Health Research Institute, Amsterdam University Medical Center, Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","reference":[{"key":"10.3233\/JAD-210319_ref1","doi-asserted-by":"crossref","first-page":"102072","DOI":"10.1016\/j.jflm.2020.102072","article-title":"COVID-19 pandemic: Coroner\u2019s database of death inquiries with clinical epidemiology and total and excess mortality analyses in the District of Kildare March to June 2020","volume":"76","author":"Cusack","year":"2020","journal-title":"J Forensic Leg Med"},{"key":"10.3233\/JAD-210319_ref2","doi-asserted-by":"crossref","first-page":"e0241030","DOI":"10.1371\/journal.pone.0241030","article-title":"COVID-19 outbreak in long-term care facilities from Spain. 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