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The precise mechanism by which the gut microbiota can affect the development of Alzheimer\u2019s disease is unknown, but the gut microbiota is thought to communicate with the brain directly via the vagus nerve or indirectly through signaling molecules such as cytokines, neuroendocrine hormones, bacterial components, neuroactive molecules, or microbial metabolites such as short-chain fatty acids. In particular, interventions such as probiotic supplementation, fecal microbiota transfer, and supplementation with microbial metabolites have been used not only to study the effects that the gut microbiota has on behavior and cognitive function, but also as potential therapeutics for Alzheimer\u2019s disease. A few of these interventions, such as probiotics, are promising candidates for the improvement of cognition in Alzheimer \u2019s disease and are the focus of this review.<\/jats:p>","DOI":"10.3233\/jad-215290","type":"journal-article","created":{"date-parts":[[2022,3,4]],"date-time":"2022-03-04T13:54:10Z","timestamp":1646402050000},"page":"17-31","source":"Crossref","is-referenced-by-count":50,"title":["Influence of the Microbiota-Gut-Brain Axis on Cognition in Alzheimer\u2019s Disease"],"prefix":"10.1177","volume":"87","author":[{"given":"Yael-Natalie H.","family":"Escobar","sequence":"first","affiliation":[{"name":"Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University College of Medicine and Wexner Medical Center, Columbus, OH, USA"},{"name":"College of Nursing, The Ohio State University, Columbus, OH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Devin","family":"O\u2019Piela","sequence":"additional","affiliation":[{"name":"Dorothy M. 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