{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T06:16:07Z","timestamp":1790662567430,"version":"4.1.0"},"reference-count":52,"publisher":"SAGE Publications","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAD"],"published-print":{"date-parts":[[2022,5,31]]},"abstract":"<jats:p>Background: It is crucial for older adults, especially those with mild cognitive impairment (MCI), to make profitable decisions routinely. However, the results regarding decision-making (DM) remain inconsistent. Objective: The present study assessed DM profiles under uncertainty conditions in individuals with MCI and their associations with multi-domain cognitive performance. Method: Fifty-three patients with MCI and forty-two age-, gender-, and education level-matched healthy controls (HCs) were administered a comprehensive neuropsychological battery test. The Iowa Gambling Task (IGT) and Game of Dice Task (GDT) were used to assess DM competence in conditions involving ambiguity and risk, respectively. In addition, Spearman\u2019s correlations were used to examine relationships between GDT and multi-domain cognitive performance. Result: The final capital (FC) and frequency of utilization of negative feedback (FUNF) and positive feedback (FUPF) in the GDT were lower in MCI patients than in HCs. In addition, the number of shifts between safe and risky alternatives was significantly different across groups. However, IGT performance was comparable across groups. In the MCI patients, risky DM performance was associated with language, whereas in HCs was correlated with memory and executive functions. Besides, in MCI, performance on IGT was significantly correlated with social cognition. Conclusion: Individuals with mild cognitive impairment have difficulty utilizing feedback to make optimal decisions under risky situations. The association between decision-making performance and cognitive function is divergent regarding situational uncertainty and individuals\u2019 cognitive status. In mild cognitive impairment and normal aging, decision-making under ambiguity needs further investigation.<\/jats:p>","DOI":"10.3233\/jad-215440","type":"journal-article","created":{"date-parts":[[2022,4,15]],"date-time":"2022-04-15T10:51:40Z","timestamp":1650019900000},"page":"1215-1227","source":"Crossref","is-referenced-by-count":10,"title":["Decision-Making Profiles and Their Associations with Cognitive Performance in Mild Cognitive Impairment"],"prefix":"10.1177","volume":"87","author":[{"given":"Ying","family":"Zhang","sequence":"first","affiliation":[{"name":"Dementia Care & Research Center, Beijing Dementia Key Lab, Peking University Institute of Mental Health (Sixth Hospital), Beijing, China"},{"name":"National Clinical Research Center for Mental Disorders, NHC Key Laboratory of Mental Health, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Wang","sequence":"additional","affiliation":[{"name":"Dementia Care & Research Center, 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