{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,6]],"date-time":"2026-09-06T10:38:11Z","timestamp":1788691091456,"version":"build-2803163510"},"reference-count":60,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2023,2,9]],"date-time":"2023-02-09T00:00:00Z","timestamp":1675900800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Alzheimer\u2019s Disease"],"published-print":{"date-parts":[[2023,3,21]]},"abstract":"<jats:sec specific-use=\"heading-level-1\">\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Hearing loss is common in people with dementia (PwD) and a modifiable risk factor for cognitive decline. Recent studies revealed that hearing loss could cause social isolation and depression, which is associated with health-related quality of life (HRQoL). However, there is a lack of knowledge about the impact of the utilization of hearing aids on these outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec specific-use=\"heading-level-1\">\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To assess whether hearing aids use might be positively associated with the progression of cognitive function, depression, and HRQoL among PwD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec specific-use=\"heading-level-1\">\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We analyzed two-year follow-up data from 258 PwD (\u226570 years, living at home). Cognitive decline was measured with Mini-Mental Status Examination (MMSE), depression using Geriatric Depression Scale (GDS), and HRQoL with Quality of Life in Alzheimer\u2019s Disease Scale (QoL-AD). The impact of hearing aid utilization on the progression of outcomes was assessed using multivariate regression models.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec specific-use=\"heading-level-1\">\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      123 patients had hearing loss (47.7%), from which\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      \u200a=\u200a54 (43.9%) used hearing aids. Patients with hearing loss were older and had a lower HRQoL than those without hearing loss. Use of hearing aids in patients with hearing loss was associated with a lower increase in depressive symptoms (b\u200a=\u200a\u20130.74, CI\n                      <jats:sup>95<\/jats:sup>\n                      \u20131.48 \u2013\u20130.01,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u200a=\u200a0.047) over time as compared to those not using hearing aids. There was no effect on PwD\u2019s cognition, and the association with higher HRQoL was significant after one, but not consistently over two years.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec specific-use=\"heading-level-1\">\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Early detection and intervention of presbycusis using hearing aids might improve mental health and HRQoL in dementia.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3233\/jad-220938","type":"journal-article","created":{"date-parts":[[2023,2,10]],"date-time":"2023-02-10T13:07:23Z","timestamp":1676034443000},"page":"629-638","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":30,"title":["Impact of Hearing Aids on Progression of Cognitive Decline, Depression, and Quality of Life Among People with Cognitive Impairment and Dementia"],"prefix":"10.1177","volume":"92","author":[{"given":"Roaa Zayed","family":"Atef","sequence":"first","affiliation":[{"name":"German Center for Neurodegenerative Diseases (DZNE)","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernhard","family":"Michalowsky","sequence":"additional","affiliation":[{"name":"German Center for Neurodegenerative Diseases (DZNE)","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anika","family":"Raedke","sequence":"additional","affiliation":[{"name":"German Center for Neurodegenerative Diseases (DZNE)","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moritz","family":"Platen","sequence":"additional","affiliation":[{"name":"German Center for Neurodegenerative Diseases (DZNE)","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wiebke","family":"Mohr","sequence":"additional","affiliation":[{"name":"German Center for Neurodegenerative Diseases (DZNE)","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franka","family":"M\u00fchlichen","sequence":"additional","affiliation":[{"name":"German Center for Neurodegenerative Diseases (DZNE)","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jochen Ren\u00e9","family":"Thyrian","sequence":"additional","affiliation":[{"name":"German Center for Neurodegenerative Diseases (DZNE)","place":["Germany"]},{"name":"University Medicine Greifswald","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wolfgang","family":"Hoffmann","sequence":"additional","affiliation":[{"name":"German Center for Neurodegenerative Diseases (DZNE)","place":["Germany"]},{"name":"University Medicine Greifswald","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,2,9]]},"reference":[{"key":"e_1_3_6_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-2667(18)30118-X"},{"key":"e_1_3_6_3_2","doi-asserted-by":"publisher","DOI":"10.18632\/aging.101045"},{"key":"e_1_3_6_4_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinternmed.2011.1408"},{"key":"e_1_3_6_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00106-004-1058-4"},{"key":"e_1_3_6_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-016-8208-y"},{"key":"e_1_3_6_7_2","unstructured":"World Health Organization (2021) Dementia. https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/dementia. 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