{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T14:44:08Z","timestamp":1788446648161,"version":"build-2803163510"},"reference-count":61,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2023,2,24]],"date-time":"2023-02-24T00:00:00Z","timestamp":1677196800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Alzheimer\u2019s Disease"],"published-print":{"date-parts":[[2023,4,4]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Physical activity (PA) has emerged as a promising approach to delay Alzheimer\u2019s disease and related dementias, but the optimal intensity of PA to improve cognitive health remains unknown.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To evaluate the association between duration and intensity of PA and cognitive domains (executive function, processing speed, and memory) in aging Americans.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>\n                      Linear regressions in hierarchical blocks for variable adjustment and the size of effect ( \u03b7\n                      <jats:sup>2<\/jats:sup>\n                      ) were analyzed by using the data of 2,377 adults (age\u200a=\u200a69.3\u00b16.7 years) from the NHANES 2011\u20132014.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Participants with 3\u20136\u200ah\/week of vigorous- and\u200a&gt;\u200a1\u200ah\/week of moderate-intensity PA scored significantly higher in executive function and processing speed domains of cognition compared to inactive peers ( \u03b7\n                      <jats:sup>2<\/jats:sup>\n                      \u200a=\u200a0.005 &amp; 0.007 respectively, p\u200a&lt;\u200a0.05). After adjustment, the beneficial effects of 1\u20133\u200ah \/week of vigorous-intensity PA became trivial for delayed recall memory domain test scores (\u03b2=\u200a0.33; 95% CI: \u20130.01,0.67; \u03b7\n                      <jats:sup>2<\/jats:sup>\n                      \u200a=\u200a0.002; p\u200a=\u200a0.56). There was no linear dose-response relationship between the cognitive test scores and weekly moderate-intensity of PA. Interestingly, higher handgrip strength and higher late-life body mass index were associated with a higher performance across all cognitive domains.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Our study supports habitual PA with superior cognition health in some but not all domains among older adults. Furthermore, increased muscle strength and higher late-life adiposity may also impact cognition.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3233\/jad-221151","type":"journal-article","created":{"date-parts":[[2023,2,24]],"date-time":"2023-02-24T11:22:16Z","timestamp":1677237736000},"page":"975-987","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":9,"title":["Relationship Between Cognitive Performance, Physical Activity, and Socio-Demographic\/Individual Characteristics Among Aging Americans"],"prefix":"10.1177","volume":"92","author":[{"given":"Imtiaz Masfique","family":"Dowllah","sequence":"first","affiliation":[{"name":"Department of Applied Physiology and Kinesiology, University of Florida, Gainesville, FL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Lopez-Alvarenga","sequence":"additional","affiliation":[{"name":"Department of Neuroscience, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gladys E.","family":"Maestre","sequence":"additional","affiliation":[{"name":"Department of Neuroscience, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulku","family":"Karabulut","sequence":"additional","affiliation":[{"name":"Department of Health and Human Performance, University of Texas Rio Grande Valley, Brownsville, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Lehker","sequence":"additional","affiliation":[{"name":"Department of Health and Biomedical Sciences, University of Texas Rio Grande Valley, Brownsville, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Murat","family":"Karabulut","sequence":"additional","affiliation":[{"name":"Department of Health and Human Performance, University of Texas Rio Grande Valley, Brownsville, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,2,24]]},"reference":[{"key":"ref001","doi-asserted-by":"publisher","DOI":"10.1038\/nrn1323"},{"key":"ref002","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-psych-120710-100328"},{"key":"ref003","doi-asserted-by":"publisher","DOI":"10.1016\/j.cger.2013.07.002"},{"key":"ref004","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291700034930"},{"key":"ref005","unstructured":"SeeleyWW, MillerBL (2018) Dementia. 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