{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T20:02:10Z","timestamp":1785528130817,"version":"3.56.0"},"reference-count":40,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2024,2,2]],"date-time":"2024-02-02T00:00:00Z","timestamp":1706832000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Alzheimer\u2019s Disease"],"published-print":{"date-parts":[[2024,2,13]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Many studies have highlighted the effect of training with mindfulness-based interventions (MBIs) on the psycho-physical rebalancing of patients suffering from various pathologies, and their families.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>In this study, the effect of a training with mindfulness-based stress reduction (MBSR) on quality of life and emotion regulation (depression) was verified in caregivers (CGs) of patients affected by Alzheimer\u2019s disease at early stage (AD-P).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>In this randomized controlled study, 22 CGs (age\u226560 years) were treated with MBIs, in particular MBSR, and 22 CGs had no treatment. Tests (T0-T1 six months) included: SF 36-Quality of Life (QoL); Caregiver Burden Inventory (CBI); FACIT-Spiritual-Well-Being; Beck Depression Inventory (BDI); Everyday Cognition scales; and Mini-Mental State Examination (for AD-P).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Significant differences emerged between T0 and T1 for CGs with MBSR in the following dimensions: Depression-BDI ( p\u200a&gt;\u200a0.001), Burden CBI-Total (0.001), CBI-Time dependent burden ( p\u200a&lt;\u200a0.001), CBI-Developmental burden ( p\u200a&lt;\u200a0.001), CBI-Physical burden ( p\u200a&lt;\u200a0.001); and pain ( p\u200a=\u200a0.002) all decreased; while CBI-Social burden ( p\u200a=\u200a0.004), QoL-Health Role Limitation ( p\u200a&lt;\u200a0.000), QoL-Role-Limitation-Emotional-Problem ( p\u200a&lt;\u200a0.000), QoL-Energy-fatigue ( p\u200a&lt;\u200a0.000), QoL-Emotional Well-Being ( p\u200a&lt;\u200a0.001), QoL-Social Well Being ( p\u200a=\u200a0.010), and QoL-General Health ( p\u200a=\u200a0.004) increased. The control group of untreated CG showed a significant worsening in the dimensions of Physical functioning ( p\u200a=\u200a0.036) and pain ( p\u200a=\u200a0.047).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>AD-CGs treated with MBI reduced their burden and depression and experienced an improvement in all the dimensions of quality of life.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3233\/jad-230284","type":"journal-article","created":{"date-parts":[[2024,2,2]],"date-time":"2024-02-02T10:48:29Z","timestamp":1706870909000},"page":"1923-1930","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Effects of Mindfulness Based Interventions in Adults and Older Adults Caregivers of Patients with Early Stage Alzheimer\u2019s Disease: A Randomized Pilot Study"],"prefix":"10.1177","volume":"97","author":[{"given":"Maria Velia","family":"Giulietti","sequence":"first","affiliation":[{"name":"Department of Neurology, Scientific and Technological Area, INRCA-IRCCS National Institute of Health and Science on Aging, Ancona, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Fabbietti","sequence":"additional","affiliation":[{"name":"Biostatistical Center, INRCA-IRCCS National Institute of Science and Health on Aging, Ancona, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberta","family":"Spatuzzi","sequence":"additional","affiliation":[{"name":"Department of Mental Health, ASP Basilicata, Potenza, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Vespa","sequence":"additional","affiliation":[{"name":"Scientific and Technological Area, Department of Neurology, INRCA-IRCCS National Institute of Health and Science on Aging, Ancona, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,2,2]]},"reference":[{"key":"ref001","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2022.901457"},{"key":"ref002","doi-asserted-by":"publisher","DOI":"10.1186\/s12913-022-07619-w"},{"key":"ref003","doi-asserted-by":"publisher","DOI":"10.1002\/gps.4965"},{"key":"ref004","first-page":"892","volume":"26","author":"Dawood S","year":"2016","journal-title":"J Coll Physicians Surg Pak"},{"key":"ref005","doi-asserted-by":"publisher","DOI":"10.1177\/08919887221093359"},{"key":"ref006","doi-asserted-by":"publisher","DOI":"10.1111\/jocn.13601"},{"key":"ref007","doi-asserted-by":"publisher","DOI":"10.1007\/s12671-020-01500-9"},{"key":"ref008","doi-asserted-by":"publisher","DOI":"10.1093\/clipsy.bph077"},{"key":"ref009","doi-asserted-by":"publisher","DOI":"10.3233\/ADR-200249"},{"key":"ref010","doi-asserted-by":"publisher","DOI":"10.1007\/s12671-020-01564-7"},{"key":"ref011","doi-asserted-by":"publisher","DOI":"10.1080\/13607863.2022.2102140"},{"key":"ref012","doi-asserted-by":"publisher","DOI":"10.1016\/j.regg.2018.09.004"},{"key":"ref013","doi-asserted-by":"publisher","DOI":"10.1037\/a0017151"},{"key":"ref014","doi-asserted-by":"publisher","DOI":"10.1080\/13607863.2023.2176820"},{"key":"ref015","doi-asserted-by":"publisher","DOI":"10.1080\/13607863.2021.1998348"},{"key":"ref016","doi-asserted-by":"publisher","DOI":"10.1080\/13607863.2022.2107175"},{"key":"ref017","doi-asserted-by":"publisher","DOI":"10.2196\/28652"},{"key":"ref018","doi-asserted-by":"publisher","DOI":"10.1016\/j.cpr.2012.10.006"},{"key":"ref019","doi-asserted-by":"publisher","DOI":"10.1016\/j.cger.2020.06.010"},{"key":"ref020","doi-asserted-by":"publisher","DOI":"10.1186\/s12906-023-04049-x"},{"key":"ref021","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.2957-12.2012"},{"key":"ref022","doi-asserted-by":"publisher","DOI":"10.1002\/gps.3790"},{"key":"ref023","doi-asserted-by":"publisher","DOI":"10.1186\/s12877-022-02754-9"},{"key":"ref024","doi-asserted-by":"publisher","DOI":"10.1080\/07317115.2022.2154728"},{"key":"ref025","doi-asserted-by":"publisher","DOI":"10.1080\/13607863.2021.1963949"},{"key":"ref026","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.34.7.939"},{"key":"ref027","doi-asserted-by":"publisher","DOI":"10.1007\/BF03337720"},{"key":"ref028","unstructured":"WareJE, KosinskiM, KellerSD (1994) SF-36 physical and mental component summary measures: A user\u2019s manual. 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