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Two reports in the Journal of Alzheimer\u2019s Disease reach the same answer: a history of brain injury appears to be a risk factor for generalized brain atrophy, which would likely increase vulnerability to the subsequent development of any variety of ADRD, or to dementia directly attributable to reduced brain mass.<\/jats:p>","DOI":"10.3233\/jad-230332","type":"journal-article","created":{"date-parts":[[2023,5,16]],"date-time":"2023-05-16T10:59:24Z","timestamp":1684234764000},"page":"963-965","source":"Crossref","is-referenced-by-count":0,"title":["If Midlife Brain Injury Is a Risk Factor for Alzheimer\u2019s Disease and Related Dementias, What Is the Neuropathologic Mechanism?"],"prefix":"10.1177","volume":"93","author":[{"given":"Lon R.","family":"White","sequence":"first","affiliation":[{"name":"Pacific Health Research and Education Institute, Honolulu, HI, 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