{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T01:03:10Z","timestamp":1783386190955,"version":"3.54.6"},"reference-count":46,"publisher":"SAGE Publications","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAD"],"published-print":{"date-parts":[[2024,5,14]]},"abstract":"<jats:p>Background: Sleep is a potentially modifiable factor associated with dementia, including Alzheimer\u2019s disease, but current evidence supporting this is insufficient. Objective: This study aimed to determine whether sleep duration and bedtime patterns are associated with the risk of dementia among middle-aged and older people. Methods: This cohort study had an eight-year follow-up period. Participants were 13,601 community-dwelling people aged 40\u201374 years living in Murakami (Niigata, Japan). Data were collected using a self-administered questionnaire. Predictors were self-reported sleep duration and bedtime, and the outcome was newly-diagnosed dementia determined using the long-term care insurance database. Covariates were demographic characteristics, body mass index, smoking, alcohol consumption, total physical activity, insomnia symptoms, disease history, and either bedtime or sleep duration. Cox proportional hazard models were used to calculate hazard ratios (HRs). Results: The mean age of participants at baseline was 59.2 years. Over a mean follow-up period of 8.0 years, 319 cases of dementia were observed. A long self-reported sleep duration relative to the reference sleep duration (7\u200ahours) was associated with increased dementia risk, with the \u201c8 hours\u201d group (adjusted HR\u200a=\u200a1.30, 95% CI:0.99\u20131.73) and \u201c\u22659 hours\u201d group (adjusted HR\u200a=\u200a1.46, 95% CI:1.00\u20132.15) having an increased risk (marginally significant) relative to the reference group. Early bedtime was associated with increased dementia risk (adjusted p for trend\u200a=\u200a0.0010), with the \u201c21\u200a:\u200a00 or earlier\u201d group (adjusted HR\u200a=\u200a1.61, 95% CI:1.14\u20132.28) having an increased risk relative to the reference (\u201c23\u200a:\u200a00\u201d). Conclusions: A long self-reported sleep duration and early bedtime are both associated with increased dementia risk in middle-aged and older people<\/jats:p>","DOI":"10.3233\/jad-231104","type":"journal-article","created":{"date-parts":[[2024,4,26]],"date-time":"2024-04-26T14:03:04Z","timestamp":1714140184000},"page":"535-547","source":"Crossref","is-referenced-by-count":6,"title":["Self-Reported Sleep Duration and Bedtime Are Associated with Dementia Risk in Community-Dwelling People Aged 40\u201374 Years: The Murakami Cohort Study"],"prefix":"10.1177","volume":"99","author":[{"given":"Irina","family":"Bulycheva","sequence":"first","affiliation":[{"name":"Division of Preventive Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yumi","family":"Watanabe","sequence":"additional","affiliation":[{"name":"Division of Preventive Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaori","family":"Kitamura","sequence":"additional","affiliation":[{"name":"Division of Preventive Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keiko","family":"Kabasawa","sequence":"additional","affiliation":[{"name":"Department of Health Promotion Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiko","family":"Saito","sequence":"additional","affiliation":[{"name":"Division of Preventive Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akemi","family":"Takahashi","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation, Niigata University of Rehabilitation, Niigata, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryosaku","family":"Kobayashi","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation, Niigata University of Rehabilitation, Niigata, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rieko","family":"Oshiki","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation, Niigata University of Rehabilitation, Niigata, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ribeka","family":"Takachi","sequence":"additional","affiliation":[{"name":"Department of Food Science and Nutrition, Nara Women\u2019s University Graduate School of Humanities and Sciences, Nara, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shoichiro","family":"Tsugane","sequence":"additional","affiliation":[{"name":"Graduate School of Public Health, International University of Health and Welfare, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Osamu","family":"Yamazaki","sequence":"additional","affiliation":[{"name":"Niigata Prefectural Government, Niigata, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kei","family":"Watanabe","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Niigata University Medical and Dental Hospital, Niigata, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazutoshi","family":"Nakamura","sequence":"additional","affiliation":[{"name":"Division of Preventive Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","reference":[{"key":"10.3233\/JAD-231104_ref1","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/S0140-6736(20)30367-6","article-title":"Dementia prevention, intervention, and care: 2020 report of the Lancet 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