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Data were drawn from the Three-City Cohort to 1) assess the screening accuracy of the QuoCo, and 2) compare its performance to that of serial MMSE tests applying different cut-offs. For the QuoCo, sensitivity was 74.2 (95% CI: 71.4\u201376.8) and specificity 84.1 (83.6\u201384.7) and for the MMSE\u200a&lt;\u200a24, 64.1 (61.1\u201367.0) and 94.8 (94.4\u201395.1), respectively; whereas overall accuracy and sensitivity was highest for MMSE cut-offs &lt;25 and &lt;26. User-friendly charts for mapping cognitive trajectories over visits with an alert for potentially \u2018abnormal\u2019 decline can be of practical use and encourage regular monitoring in primary care where the &lt;24 cut-off is still widely used despite its poor sensitivity.<\/jats:p>","DOI":"10.3233\/jad-231176","type":"journal-article","created":{"date-parts":[[2024,2,20]],"date-time":"2024-02-20T11:22:00Z","timestamp":1708428120000},"page":"403-409","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Mapping Cognitive Trajectories and Detecting Early Dementia Using the Mini-Mental State Examination Cognitive Charts: Application to the French Three-City Cohort"],"prefix":"10.1177","volume":"98","author":[{"given":"Joanna","family":"Norton","sequence":"first","affiliation":[{"name":"Institute for Neurosciences of Montpellier (INM), Inserm, University of Montpellier, Montpellier, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laure-Anne","family":"Gutierrez","sequence":"additional","affiliation":[{"name":"Institute for Neurosciences of Montpellier (INM), Inserm, University of Montpellier, Montpellier, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Gourdeau","sequence":"additional","affiliation":[{"name":"Department of Physics, C\u00e9gep Limoilou, Qu\u00e9bec City, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H\u00e9l\u00e8ne","family":"Amieva","sequence":"additional","affiliation":[{"name":"INSERM, Bordeaux Population Health Research Center, UMR U1219, University of Bordeaux, Bordeaux, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick","family":"Bernier","sequence":"additional","affiliation":[{"name":"Specialised Geriatric Services, CIUSSS Capitale-Nationale, Qu\u00e9bec City, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudine","family":"Berr","sequence":"additional","affiliation":[{"name":"Institute for Neurosciences of Montpellier (INM), Inserm, University of Montpellier, Montpellier, France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,2,19]]},"reference":[{"key":"e_1_3_5_2_2","unstructured":"GauthierS WebsterC ServaesS MoraisJA Rosa-NetoP(2022) World Alzheimer Report 2022: Life after diagnosis: Navigating treatment care and support. 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