{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T06:29:39Z","timestamp":1787812179007,"version":"build-2784847793"},"reference-count":90,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2024,4,26]],"date-time":"2024-04-26T00:00:00Z","timestamp":1714089600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Alzheimer\u2019s Disease"],"published-print":{"date-parts":[[2024,4,30]]},"abstract":"<jats:sec specific-use=\"heading-level-1\">\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Psychosis, characterized by delusions and\/or hallucinations, is frequently observed during the progression of Alzheimer\u2019s disease (AD) and other neurodegenerative dementias (ND) (i.e., dementia with Lewy bodies (DLB), and frontotemporal dementia (FTD)) and cause diagnostic and management difficulties.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec specific-use=\"heading-level-1\">\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>This review aims at presenting a concise and up-to-date overview of psychotic symptoms that occur in patients with ND with a comparative approach.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec specific-use=\"heading-level-1\">\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A systematic review was conducted following the PRISMA guidelines. 98 original studies investigating psychosis phenotypes in neurodegenerative dementias were identified (40 cohort studies, 57 case reports).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec specific-use=\"heading-level-1\">\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Psychosis is a frequently observed phenomenon during the course of ND, with reported prevalence ranging from 22.5% to 54.1% in AD, 55.9% to 73.9% in DLB, and 18% to 42% in FTD. Throughout all stages of these diseases, noticeable patterns emerge depending on their underlying causes. Misidentification delusions (16.6\u201378.3%) and visual hallucinations (50\u201369.6%) are frequently observed in DLB, while paranoid ideas and somatic preoccupations seem to be particularly common in AD and FTD, (respectively 9.1\u201360.3% and 3.10\u201341.5%). Limited data were found regarding psychosis in the early stages of these disorders.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec specific-use=\"heading-level-1\">\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Literature data suggest that different ND are associated with noticeable variations in psychotic phenotypes, reflecting disease-specific tendencies. Further studies focusing on the early stages of these disorders are necessary to enhance our understanding of early psychotic manifestations associated with ND and help in differential diagnosis issues.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3233\/jad-231363","type":"journal-article","created":{"date-parts":[[2024,4,26]],"date-time":"2024-04-26T14:04:07Z","timestamp":1714140247000},"page":"85-99","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":15,"title":["Psychosis in Neurodegenerative Dementias: A Systematic Comparative Review"],"prefix":"10.1177","volume":"99","author":[{"given":"Coralie","family":"Cressot","sequence":"first","affiliation":[{"name":"Universit\u00e9 Paris Cit\u00e9, UMRS 1144, INSERM, Paris, France"},{"name":"Centre de Neurologie Cognitive, AP-HP.Nord, Site Lariboisi\u00e8re Fernand-Widal, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agathe","family":"Vrillon","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris Cit\u00e9, UMRS 1144, INSERM, Paris, France"},{"name":"Centre de Neurologie Cognitive, AP-HP.Nord, Site Lariboisi\u00e8re Fernand-Widal, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthieu","family":"Lilamand","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris Cit\u00e9, UMRS 1144, INSERM, Paris, France"},{"name":"Service de G\u00e9riatrie, AP-HP.Nord, Site Lariboisi\u00e8re Fernand-Widal, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H\u00e9l\u00e8ne","family":"Francisque","sequence":"additional","affiliation":[{"name":"Centre de Neurologie Cognitive, AP-HP.Nord, Site Lariboisi\u00e8re Fernand-Widal, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aur\u00e9lie","family":"M\u00e9auzoone","sequence":"additional","affiliation":[{"name":"Centre de Neurologie Cognitive, AP-HP.Nord, Site Lariboisi\u00e8re Fernand-Widal, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire","family":"Hourregue","sequence":"additional","affiliation":[{"name":"Centre de Neurologie Cognitive, AP-HP.Nord, Site Lariboisi\u00e8re Fernand-Widal, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julien","family":"Dumurgier","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris Cit\u00e9, UMRS 1144, INSERM, Paris, France"},{"name":"Universit\u00e9 Paris Cit\u00e9, Inserm U1153, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emeline","family":"Marlinge","sequence":"additional","affiliation":[{"name":"D\u00e9partement de Psychiatrie, AP-HP.Nord, Site Lariboisi\u00e8re Fernand-Widal, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire","family":"Paquet","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris Cit\u00e9, UMRS 1144, INSERM, Paris, France"},{"name":"Centre de Neurologie Cognitive, AP-HP.Nord, Site Lariboisi\u00e8re Fernand-Widal, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmanuel","family":"Cognat","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris Cit\u00e9, UMRS 1144, INSERM, Paris, France"},{"name":"Centre de Neurologie Cognitive, AP-HP.Nord, Site Lariboisi\u00e8re Fernand-Widal, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,4,26]]},"reference":[{"key":"e_1_3_6_2_2","doi-asserted-by":"publisher","DOI":"10.1212\/01.CON.0000466662.89908.e7"},{"key":"e_1_3_6_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awaa413"},{"key":"e_1_3_6_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/WNN.0000000000000189"},{"key":"e_1_3_6_5_2","doi-asserted-by":"publisher","DOI":"10.1080\/13554794.2016.1187178"},{"key":"e_1_3_6_6_2","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2013-203458"},{"key":"e_1_3_6_7_2","first-page":"266","article-title":"Schizophrenia or frontotemporal dementia in a young Chinese female: A purview of possible diagnoses","volume":"22","author":"Grewal GS","year":"2011","unstructured":"GrewalGS, KanagasundramS, JambunathanS (2011) Schizophrenia or frontotemporal dementia in a young Chinese female: A purview of possible diagnoses. 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