{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T04:04:52Z","timestamp":1787025892886,"version":"build-2736575974"},"reference-count":39,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2024,7,8]],"date-time":"2024-07-08T00:00:00Z","timestamp":1720396800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Alzheimer\u2019s Disease"],"published-print":{"date-parts":[[2024,7,30]]},"abstract":"<jats:sec specific-use=\"heading-level-1\">\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Older adults with heart failure are at elevated risk of Alzheimer\u2019s disease and related dementias (AD\/ADRD). Research suggests that insomnia and depressive episodes contribute somewhat dissociable impacts on risk for AD\/ADRD in this patient population, although the temporal ordering of effects is unknown.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec specific-use=\"heading-level-1\">\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>This study examined time to dementia diagnosis among patients with comorbid insomnia and\/or depressive episodes in an epidemiological sample.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec specific-use=\"heading-level-1\">\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Secondary data analyses were conducted using a cohort study of 203,819 Veterans with a primary admission diagnosis of heart failure in 129 VA Medical Centers.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec specific-use=\"heading-level-1\">\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Patients with diagnoses of both insomnia and depressive episodes had the shortest time to a dementia diagnosis at both 1-year (Hazard ratio\u200a=\u200a1.43, 95% CI [1.36, 1.51]) and 3-year follow-up time points (Hazard ratio\u200a=\u200a1.40, 95% CI [1.34, 1.47]) versus patients with one or neither comorbidity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec specific-use=\"heading-level-1\">\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Individuals with both comorbidities had the shortest time to dementia onset. Screening for these comorbidities may help to identify patients at elevated risk of dementia who could benefit from enhanced monitoring or early intervention strategies for more rapid detection and management of dementia symptoms.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3233\/jad-240080","type":"journal-article","created":{"date-parts":[[2024,7,12]],"date-time":"2024-07-12T10:48:46Z","timestamp":1720781326000},"page":"899-909","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Time to Dementia Diagnosis Among Veterans with Comorbid Insomnia and Depressive Episodes"],"prefix":"10.1177","volume":"100","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6605-4648","authenticated-orcid":false,"given":"Melanie L.","family":"Bozzay","sequence":"first","affiliation":[{"name":"The Ohio State University Wexner Medical 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