{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T18:07:33Z","timestamp":1780423653075,"version":"3.54.1"},"reference-count":82,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2024,6,28]],"date-time":"2024-06-28T00:00:00Z","timestamp":1719532800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Alzheimer\u2019s Disease"],"published-print":{"date-parts":[[2024,7,30]]},"abstract":"<jats:p>\n                    This manuscript reviews the significant skin manifestations of Lewy body disease, including Parkinson\u2019s disease and dementia with Lewy bodies, and the diagnostic utility of skin biopsy. Besides classic motor and cognitive symptoms, non-motor manifestations, particularly dermatologic disorders, can play a crucial role in disease presentation and diagnosis. This review explores the intricate relationship between the skin and Lewy body disease. Seborrheic dermatitis, autoimmune blistering diseases (bullous pemphigoid and pemphigus), rosacea, and melanoma are scrutinized for their unique associations with Parkinson\u2019s disease, revealing potential links through shared pathophysiological mechanisms. Advances in diagnostic techniques allow the identification of promising biomarkers such as\n                    <jats:italic toggle=\"yes\">\u03b1<\/jats:italic>\n                    -synuclein in samples obtained by skin punch biopsy. Understanding the dermatologic aspects of Lewy body disease not only contributes to its holistic characterization but also holds implications for innovative diagnostic approaches.\n                  <\/jats:p>","DOI":"10.3233\/jad-240198","type":"journal-article","created":{"date-parts":[[2024,7,2]],"date-time":"2024-07-02T12:14:40Z","timestamp":1719922480000},"page":"761-769","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["The Skin and Lewy Body Disease"],"prefix":"10.1177","volume":"100","author":[{"given":"Lydia","family":"Cassard","sequence":"first","affiliation":[{"name":"Cleveland Clinic Lerner College of Medicine","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Golara","family":"Honari","sequence":"additional","affiliation":[{"name":"Stanford University School of Medicine","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Babak","family":"Tousi","sequence":"additional","affiliation":[{"name":"Cleveland Clinic Lerner College of Medicine","place":["USA"]},{"name":"Neurological Institute","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,6,28]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(15)00462-6"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(19)30153-X"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/NEN.0b013e318186de48"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2019.03.003"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awn102"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2016.08.001"},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(15)00396-8"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2008.08748.x"},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.1021\/acscentsci.8b00879"},{"key":"e_1_3_4_11_2","doi-asserted-by":"publisher","DOI":"10.1021\/acscentsci.0c01028"},{"key":"e_1_3_4_12_2","doi-asserted-by":"publisher","DOI":"10.3390\/metabo11120819"},{"key":"e_1_3_4_13_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-021-21669-4"},{"key":"e_1_3_4_14_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacsau.2c00300"},{"key":"e_1_3_4_15_2","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.17826"},{"key":"e_1_3_4_16_2","doi-asserted-by":"publisher","DOI":"10.3988\/jcn.2022.18.6.628"},{"key":"e_1_3_4_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2020.11.017"},{"key":"e_1_3_4_18_2","first-page":"311","article-title":"Effect of L-dopa on seborrhea of Parkinsonism","volume":"2","author":"Appenzeller O","year":"1970","unstructured":"AppenzellerO, HarvilleD (1970) Effect of L-dopa on seborrhea of Parkinsonism. 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