{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T16:15:19Z","timestamp":1785255319348,"version":"3.55.0"},"reference-count":34,"publisher":"SAGE Publications","issue":"s1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAD"],"published-print":{"date-parts":[[2024,8,20]]},"abstract":"<jats:p>Social dysfunction is a maladaptive process of coping, problem solving, and achieving one\u2019s goals. A new definition of apathy was cross-linked to social dysfunction, with a reduced goal-directed behavior and social interaction as a separate dimension. We hypothesized that these two neuropsychiatric symptoms may be included in the mild behavioral impairment diagnostic framework, operationalizing and standardizing late-life neuropsychiatric symptom assessment, to improve risk determination of dementia. Social dysfunction and apathy were transdiagnostic and prodromic for late-life cognitive disorders. A transdiagnostic approach could provide a useful mean for a better understanding of apathy and related conditions such as social behavior.<\/jats:p>","DOI":"10.3233\/jad-240556","type":"journal-article","created":{"date-parts":[[2024,7,19]],"date-time":"2024-07-19T11:51:08Z","timestamp":1721389868000},"page":"S57-S61","source":"Crossref","is-referenced-by-count":8,"title":["Social Dysfunction and Apathy: Transdiagnostic Domains in Late-Life Cognitive Disorders"],"prefix":"10.1177","volume":"100","author":[{"given":"Madia","family":"Lozupone","sequence":"first","affiliation":[{"name":"Department of Translational Biomedicine and Neuroscience \u201cDiBrain\u201d, University of Bari Aldo Moro, Bari, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vittorio","family":"Dibello","sequence":"additional","affiliation":[{"name":"\u201cCesare Frugoni\u201d Internal and Geriatric Medicine and Memory Unit, University of Bari \u201cAldo Moro\u201d, Bari, Italy"},{"name":"Department of Orofacial Pain and Dysfunction, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodolfo","family":"Sardone","sequence":"additional","affiliation":[{"name":"Local Healthcare Authority of Taranto, Taranto, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario","family":"Altamura","sequence":"additional","affiliation":[{"name":"Psychiatric Unit, Department of Clinical & Experimental Medicine, University of Foggia, Foggia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonello","family":"Bellomo","sequence":"additional","affiliation":[{"name":"Psychiatric Unit, Department of Clinical & Experimental Medicine, University of Foggia, Foggia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Daniele","sequence":"additional","affiliation":[{"name":"Department of Neuroscience, Catholic University of Sacred Heart, Rome, Italy"},{"name":"Neurology Unit, IRCCS Fondazione Policlinico Universitario A. 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