{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T06:31:00Z","timestamp":1787898660809,"version":"build-2784847793"},"reference-count":14,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2021,9,7]],"date-time":"2021-09-07T00:00:00Z","timestamp":1630972800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Huntington's Disease"],"published-print":{"date-parts":[[2021,9,7]]},"abstract":"<jats:p>The R6\/2 murine model of Huntington\u2019s disease (HD) is extensively used in HD research. The current study replicates and extends previous work assessing the impact of housing R6\/2 mice with healthy wild-type (WT) littermates on disease progression. The current study extends the previous finding by including male cohorts and the use of a standard diet and water regimen, as opposed to the enhanced diet used in the previous study. This study found that the inclusion of healthy wild-type (WT) littermates, alone, improved survivabilty in R6\/2 mice, but did not have a significant impact on weight loss.<\/jats:p>","DOI":"10.3233\/jhd-210474","type":"journal-article","created":{"date-parts":[[2021,9,10]],"date-time":"2021-09-10T13:14:56Z","timestamp":1631279696000},"page":"455-458","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Housing R6\/2 Mice with Wild-Type Littermates Increases Lifespan"],"prefix":"10.1177","volume":"10","author":[{"given":"Darren","family":"Story","sequence":"first","affiliation":[{"name":"Field Neurosciences Institute for Restorative Neurology, Central Michigan University, Mount Pleasant, MI, USA"},{"name":"Department of Psychology, Central Michigan University, Mount Pleasant, MI, 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