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Objective: The aim of this study was to investigate the lived experiences of depression in people with the CAG expansion for HD using qualitative methods. Methods: We conducted semi-structured interviews with HD CAG expansion carriers who had current or previous experiences of depression, until data saturation was achieved. This resulted in interviews from 17 HD CAG expansion carriers (11 premanifest, 6 manifest) which were analyzed using thematic analysis. Results: The four key themes that emerged related to the temporal characteristics of depression in HD, the qualitative changes associated with depression, psychosocial stressors perceived to contribute to depression, and the perception of depression as an endogenous feature of HD. Conclusion: This study provides an enriched understanding of the unique characteristics of depression in HD, and the attributions that CAG expansion carriers make for their depression symptoms. The themes identified in this study can be used to guide more targeted assessment and treatment of depression in HD.<\/jats:p>","DOI":"10.3233\/jhd-220537","type":"journal-article","created":{"date-parts":[[2022,5,13]],"date-time":"2022-05-13T12:22:37Z","timestamp":1652444557000},"page":"321-335","source":"Crossref","is-referenced-by-count":14,"title":["The Lived Experiences of Depression in Huntington\u2019s Disease: A Qualitative Study"],"prefix":"10.1177","volume":"11","author":[{"given":"Hiba","family":"Bilal","sequence":"first","affiliation":[{"name":"School of Psychological Sciences, and Turner Institute for Brain and Mental Health, Monash University, Clayton, Victoria, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Narelle","family":"Warren","sequence":"additional","affiliation":[{"name":"School of Social Sciences, Monash University, Clayton, Victoria, 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