{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T11:33:52Z","timestamp":1788176032321,"version":"build-2803163510"},"reference-count":35,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2024,8,14]],"date-time":"2024-08-14T00:00:00Z","timestamp":1723593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Huntington's Disease"],"published-print":{"date-parts":[[2024,9,10]]},"abstract":"<jats:sec specific-use=\"heading-level-1\">\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Huntington\u2019s disease (HD) presents patients and individuals at risk for HD with significant levels of stress. However, relatively little research has examined how individuals cope with stress related to the disease or the association of specific coping strategies with psychological symptoms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec specific-use=\"heading-level-1\">\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>This study examined the ways in which HD patients and at-risk individuals cope with HD-related stress using a control-based model of coping and the association of coping strategies with symptoms of depression and anxiety.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec specific-use=\"heading-level-1\">\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>\n                      HD patients (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      \u200a=\u200a49) and at-risk individuals (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      \u200a=\u200a76) completed the Responses to Stress Questionnaire \u2013 Huntington\u2019s Disease Version to assess coping strategies in response to HD-related stress, as well as standardized measures of depression and anxiety symptoms. Patient health records were accessed to obtain information related to disease characteristics.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec specific-use=\"heading-level-1\">\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Patients and at-risk individuals reported using comparable levels of primary control coping, secondary control coping, and disengagement coping strategies. In linear regression analyses, only secondary control coping was significantly associated with lower depression (\n                      <jats:italic toggle=\"yes\">\u03b2<\/jats:italic>\n                      =\u200a\u20130.62,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u200a&lt;\u200a0.001) and anxiety (\n                      <jats:italic toggle=\"yes\">\u03b2<\/jats:italic>\n                      =\u200a\u20130.59,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u200a&lt;\u200a0.001) symptoms in patients and at-risk individuals (\n                      <jats:italic toggle=\"yes\">\u03b2<\/jats:italic>\n                      =\u200a\u20130.55,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u200a&lt;\u200a0.001 and\n                      <jats:italic toggle=\"yes\">\u03b2<\/jats:italic>\n                      =\u200a\u20130.50,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u200a&lt;\u200a0.001, respectively).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec specific-use=\"heading-level-1\">\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Secondary control coping may be beneficial for both HD patients and at-risk individuals. Future research using the control-based model of coping in longitudinal studies with the HD population is needed, and future interventions could test the effects of cognitive reframing and acceptance as coping strategies for families affected by HD.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3233\/jhd-240027","type":"journal-article","created":{"date-parts":[[2024,8,16]],"date-time":"2024-08-16T11:55:23Z","timestamp":1723809323000},"page":"339-347","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Coping with Huntington\u2019s Disease in Patients and At-Risk Individuals"],"prefix":"10.1177","volume":"13","author":[{"given":"Abigail L.B.","family":"Snow","sequence":"first","affiliation":[{"name":"Vanderbilt University","place":["USA"]},{"name":"Vanderbilt University Medical Center","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abagail 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