{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T02:27:49Z","timestamp":1790216869312,"version":"4.1.0"},"reference-count":29,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2021,5,19]],"date-time":"2021-05-19T00:00:00Z","timestamp":1621382400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Neuromuscular Diseases"],"published-print":{"date-parts":[[2021,7,30]]},"abstract":"<jats:p>We describe the development of a new tool specifically designed to record oral abilities, swallowing and, more generally, feeding in young type 1 SMA patients, to be used during the first 24 months of life.<\/jats:p>\n                  <jats:p>The tool is composed by a checklist and a separate section summarizing the functional abilities into levels of feeding\/swallowing impairment. The checklist includes 12 questions assessing aspects thought to be clinically meaningful for a type 1 SMA population and developmentally appropriate for infants during the first months of life. Each item is graded with a score of 0 or 1, depending on the child\u2019s ability to perform the activity. As some items are age-dependent, the number of items to be used, and therefore the maximum score, changes with increasing age. The levels of feeding\/swallowing impairment include four levels that can be identified using easily identifiable clinical criteria.<\/jats:p>\n                  <jats:p>In an attempt to validate the tool in an untreated population we applied it to 24 type 1 SMA patients (age range: 2.3\u201324.1 months, mean: 10.8) in whom the same information collected by the new tool had been previously recorded using a less-structured format.<\/jats:p>\n                  <jats:p>When patients were classified in three groups according to the Dubowitz decimal classification, there was a significant difference both at baseline and at follow-up ( p\u200a&lt;\u200a0.001). The items assessing fatigue during the nursing sessions were the most frequently impaired even in infants who did not have any other obvious clinical sign of swallowing difficulties.<\/jats:p>","DOI":"10.3233\/jnd-200614","type":"journal-article","created":{"date-parts":[[2021,5,21]],"date-time":"2021-05-21T13:22:39Z","timestamp":1621603359000},"page":"589-601","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":37,"title":["Oral and Swallowing Abilities Tool (OrSAT) for Type 1 SMA Patients: Development of a New Module"],"prefix":"10.1177","volume":"8","author":[{"given":"Beatrice","family":"Berti","sequence":"first","affiliation":[{"name":"Centro Clinico Nemo, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lavinia","family":"Fanelli","sequence":"additional","affiliation":[{"name":"Centro Clinico Nemo, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"de Sanctis","sequence":"additional","affiliation":[{"name":"Centro Clinico Nemo, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberta","family":"Onesimo","sequence":"additional","affiliation":[{"name":"Pediatric Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Concetta","family":"Palermo","sequence":"additional","affiliation":[{"name":"Centro Clinico Nemo, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Leone","sequence":"additional","affiliation":[{"name":"Centro Clinico Nemo, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Carnicella","sequence":"additional","affiliation":[{"name":"Centro Clinico Nemo, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giulia","family":"Norcia","sequence":"additional","affiliation":[{"name":"Centro Clinico Nemo, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicola","family":"Forcina","sequence":"additional","affiliation":[{"name":"Centro Clinico Nemo, Fondazione Policlinico Universitario A. 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Gemelli IRCCS, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Finkel","sequence":"additional","affiliation":[{"name":"St. Jude Children\u2019s Research Hospital, Memphis, Tennessee, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marika","family":"Pane","sequence":"additional","affiliation":[{"name":"Centro Clinico Nemo, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy"},{"name":"Child Neurology and Psychiatry, Catholic University of Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eugenio","family":"Mercuri","sequence":"additional","affiliation":[{"name":"Centro Clinico Nemo, Fondazione Policlinico Universitario A. 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