{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T01:10:08Z","timestamp":1777857008432,"version":"3.51.4"},"reference-count":24,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Neuromuscular Diseases"],"published-print":{"date-parts":[[2021,7,30]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Expert guidelines recommend annual monitoring of 25-hydroxyvitamin D (25-OHD) and maintaining 25-OHD \u226530\u200ang\/ml in patients with dystrophinopathies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>We hypothesized that 25-OHD remains stable and requires less frequent monitoring in patients taking stable maintenance doses of vitamin D.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We performed a retrospective cohort study, using the electronic health record to identify 26 patients with dystrophinopathies with a baseline 25-OHD \u226530\u200ang\/mL and at least one additional 25-OHD measurement. These patients had received a stable dose of vitamin D for \u22653 months prior to their baseline 25-OHD measurement and throughout follow-up. The main outcome measured was the mean duration time the subjects spent with a 25-OHD \u226530 ng\/mL.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Only 19% of patients dropped their 25-OHD to &lt;\u200a30\u200ang\/ml, with a mean time to drop of 33 months and a median nadir 25-OHD of 28\u200ang\/mL.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>These results suggest that measurement of 25-OHD every 2\u20132.5 years may be sufficient in patients with a baseline 25-OHD \u226530\u200ang\/mL and who are on a stable maintenance dose of vitamin D. Other patients may require more frequent assessments.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3233\/jnd-200625","type":"journal-article","created":{"date-parts":[[2021,4,2]],"date-time":"2021-04-02T14:40:06Z","timestamp":1617374406000},"page":"481-487","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Vitamin D Level Stability in Dystrophinopathy Patients on Vitamin D Supplementation"],"prefix":"10.1177","volume":"8","author":[{"given":"Naomi","family":"Vather-Wu","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, University of Iowa, Iowa City, IA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew D.","family":"Krasowski","sequence":"additional","affiliation":[{"name":"Department of Pathology, University of Iowa, Iowa City, IA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katherine D.","family":"Mathews","sequence":"additional","affiliation":[{"name":"Department of Neurology, University of Iowa, Iowa City, IA, USA"},{"name":"Department of Pediatrics, University of Iowa, Iowa City, IA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amal","family":"Shibli-Rahhal","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, University of Iowa, Iowa City, IA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2021,4,1]]},"reference":[{"key":"ref001","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2014-2044"},{"key":"ref002","doi-asserted-by":"publisher","DOI":"10.2147\/AHMT.S125739"},{"key":"ref003","doi-asserted-by":"publisher","DOI":"10.1016\/j.nmd.2018.06.014"},{"key":"ref004","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(18)30025-5"},{"key":"ref005","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD003725.pub2"},{"key":"ref006","doi-asserted-by":"publisher","DOI":"10.1016\/s0002-9149(02)03429-x"},{"key":"ref007","doi-asserted-by":"publisher","DOI":"10.1002\/mus.23948"},{"key":"ref008","doi-asserted-by":"publisher","DOI":"10.1002\/mus.23948"},{"key":"ref009","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410160206"},{"key":"ref010","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410120314"},{"key":"ref011","doi-asserted-by":"publisher","DOI":"10.1096\/fj.06-7285"},{"key":"ref012","doi-asserted-by":"publisher","DOI":"10.1007\/s00391-019-01573-9"},{"key":"ref013","doi-asserted-by":"publisher","DOI":"10.1055\/a-0851-9737"},{"key":"ref014","doi-asserted-by":"publisher","DOI":"10.1007\/s11657-019-0589-y"},{"key":"ref015","doi-asserted-by":"publisher","DOI":"10.1016\/j.rdc.2012.03.010"},{"key":"ref016","doi-asserted-by":"publisher","DOI":"10.17226\/13050"},{"key":"ref017","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-014-2687-4"},{"key":"ref018","doi-asserted-by":"publisher","DOI":"10.3390\/nu5093605"},{"key":"ref019","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/69.5.842"},{"key":"ref020","doi-asserted-by":"publisher","DOI":"10.5858\/arpa.2018-0625-CP"},{"key":"ref021","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsbmb.2019.03.015"},{"key":"ref022","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2011-0385"},{"key":"ref023","doi-asserted-by":"publisher","DOI":"10.1592\/phco.30.3.254"},{"key":"ref024","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2006-0710"}],"container-title":["Journal of Neuromuscular Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.3233\/JND-200625","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.3233\/JND-200625","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.3233\/JND-200625","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T23:49:41Z","timestamp":1777506581000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.3233\/JND-200625"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4,1]]},"references-count":24,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021,7,30]]}},"alternative-id":["10.3233\/JND-200625"],"URL":"https:\/\/doi.org\/10.3233\/jnd-200625","relation":{},"ISSN":["2214-3599","2214-3602"],"issn-type":[{"value":"2214-3599","type":"print"},{"value":"2214-3602","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,4,1]]}}}