{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T04:05:00Z","timestamp":1787025900159,"version":"build-2736575974"},"reference-count":25,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2019,6,14]],"date-time":"2019-06-14T00:00:00Z","timestamp":1560470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Parkinson\u2019s Disease"],"published-print":{"date-parts":[[2019,7,30]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Although several studies have reported a correlation between Beh\u00e7et\u2019s disease (BD) and Parkinson\u2019s disease, this association has not yet been clarified.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To determine the risk of Parkinson\u2019s disease in patients with BD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>BD patients ( n\u200a=\u200a17,179; mean age, 51.12\u00b18.09 years; male, 34.95%) without known previous diagnosis of Parkinson\u2019s disease were selected from the Korean National Health Insurance Database between 2010 and 2013. An age- and gender-matched control population of individuals without BD was randomly sampled at a ratio of 3:1 ( n\u200a=\u200a34,575). Both cohorts were followed for development of Parkinson\u2019s disease until 2015.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Among a total of 11,525 BD patients, 50 (0.43%) developed Parkinson\u2019s disease, whereas only 51 among the 34,575 individuals in the non-BD group developed Parkinson\u2019s (0.15%, P\u200a&lt;\u200a0.0001). The incidence of Parkinson\u2019s disease was significantly higher in BD patients than in controls. In addition, during the follow-up period, patients with BD were more likely to be diagnosed with Parkinson\u2019s disease than those in the non-BD group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>BD patients had a higher risk of Parkinson\u2019s disease compared to non-BD controls. Physicians should carefully monitor patients with BD for potential development of Parkinson\u2019s disease.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3233\/jpd-191622","type":"journal-article","created":{"date-parts":[[2019,6,18]],"date-time":"2019-06-18T12:25:34Z","timestamp":1560860734000},"page":"583-589","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Risk for Parkinson\u2019s Disease in Patients with Beh\u00e7et\u2019s Disease: A Nationwide Population-Based Dynamic Cohort Study in Korea"],"prefix":"10.1177","volume":"9","author":[{"given":"Ho Youn","family":"Park","sequence":"first","affiliation":[{"name":"Department of Orthopedics, Uijeongbu St. Mary\u2019s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ju Hee","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Uijeongbu St. Mary\u2019s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soo Young","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Uijeongbu St. Mary\u2019s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong Soo","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Uijeongbu St. Mary\u2019s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyung-Do","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, College of Medicine, The Catholic University of Korea, Seoul,  Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong Gyu","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, College of Medicine, The Catholic University of Korea, Seoul,  Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young Bok","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Uijeongbu St. Mary\u2019s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2019,6,14]]},"reference":[{"key":"ref001","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2017.09.035"},{"key":"ref002","doi-asserted-by":"publisher","DOI":"10.1017\/S0317167100033552"},{"key":"ref003","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.14601"},{"key":"ref004","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(09)70015-8"},{"key":"ref005","doi-asserted-by":"publisher","DOI":"10.1007\/s10238-014-0328-z"},{"key":"ref006","first-page":"S19","volume":"21","author":"Zouboulis CC","year":"2003","journal-title":"Clin Exp 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