{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T16:45:51Z","timestamp":1790095551181,"version":"4.0.1"},"reference-count":197,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2021,8,2]],"date-time":"2021-08-02T00:00:00Z","timestamp":1627862400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JPD"],"published-print":{"date-parts":[[2021,8,2]]},"abstract":"<jats:p>Sleep disturbances are among the common nonmotor symptoms in patients with Parkinson\u2019s disease (PD). Sleep can be disrupted by nocturnal motor and nonmotor symptoms and other comorbid sleep disorders. Rapid eye movement sleep behavior disorder (RBD) causes sleep-related injury, has important clinical implications as a harbinger of PD and predicts a progressive clinical phenotype. Restless legs syndrome (RLS) and its related symptoms can impair sleep initiation. Excessive daytime sleepiness (EDS) is a refractory problem affecting patients\u2019 daytime activities. In particular, during the COVID-19 era, special attention should be paid to monitoring sleep problems, as infection-prevention procedures for COVID-19 can affect patients\u2019 motor symptoms, psychiatric symptoms and sleep. Therefore, screening for and managing sleep problems is important in clinical practice, and the maintenance of good sleep conditions may improve the quality of life of PD patients. This narrative review focused on the literature published in the past 10 years, providing a current update of various sleep disturbances in PD patients and their management, including RBD, RLS, EDS, sleep apnea and circadian abnormalities.<\/jats:p>","DOI":"10.3233\/jpd-202425","type":"journal-article","created":{"date-parts":[[2021,4,23]],"date-time":"2021-04-23T17:03:52Z","timestamp":1619197432000},"page":"971-992","source":"Crossref","is-referenced-by-count":31,"title":["Current Update on Clinically Relevant Sleep Issues in Parkinson\u2019s Disease: A Narrative Review"],"prefix":"10.1177","volume":"11","author":[{"given":"Keisuke","family":"Suzuki","sequence":"first","affiliation":[{"name":"Department of Neurology, Dokkyo Medical University, Shimotsuga, Tochigi, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","reference":[{"key":"10.3233\/JPD-202425_ref1","doi-asserted-by":"publisher","DOI":"10.1177\/0891988720964250"},{"key":"10.3233\/JPD-202425_ref2","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1016\/S0140-6736(20)30185-9","article-title":"A novel coronavirus outbreak of global health concern","volume":"395","author":"Wang","year":"2020","journal-title":"Lancet"},{"key":"10.3233\/JPD-202425_ref3","doi-asserted-by":"crossref","first-page":"4779","DOI":"10.3390\/ijerph17134779","article-title":"Effects of Covid-19 lockdown on mental health and sleep disturbances in Italy","volume":"17","author":"Gualano","year":"2020","journal-title":"Int J Environ Res Public Health"},{"key":"10.3233\/JPD-202425_ref4","doi-asserted-by":"crossref","first-page":"102052","DOI":"10.1016\/j.ajp.2020.102052","article-title":"Chinese mental health burden during the COVID-19 pandemic","volume":"51","author":"Huang","year":"2020","journal-title":"Asian J Psychiatr"},{"key":"10.3233\/JPD-202425_ref5","first-page":"1","article-title":"Sleep neurologists call it \u2018COVID-somnia\u2019\u2014Increased sleep disturbances linked to the pandemic","volume":"20","author":"Hurley","year":"2020","journal-title":"Neurol Today"},{"key":"10.3233\/JPD-202425_ref6","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1038\/s41531-020-00128-9","article-title":"Synergy of pandemics-social isolation is associated with worsened Parkinson severity and quality of life","volume":"6","author":"Subramanian","year":"2020","journal-title":"NPJ Parkinsons Dis"},{"key":"10.3233\/JPD-202425_ref7","doi-asserted-by":"crossref","first-page":"351","DOI":"10.3233\/JPD-202038","article-title":"The impact of the COVID-19 pandemic on Parkinson\u2019s disease: Hidden sorrows and emerging opportunities","volume":"10","author":"Helmich","year":"2020","journal-title":"J Parkinsons Dis"},{"key":"10.3233\/JPD-202425_ref8","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1016\/j.sleep.2020.09.011","article-title":"Investigation on sleep and mental health of patients with Parkinson\u2019s disease during the Coronavirus disease 2019 pandemic","volume":"75","author":"Xia","year":"2020","journal-title":"Sleep Med"},{"key":"10.3233\/JPD-202425_ref9","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1212\/WNL.58.7.1019","article-title":"Parkinson\u2019s disease and sleepiness: An integral part of PD","volume":"58","author":"Arnulf","year":"2002","journal-title":"Neurology"},{"key":"10.3233\/JPD-202425_ref10","doi-asserted-by":"crossref","first-page":"zsz004","DOI":"10.1093\/sleep\/zsz004","article-title":"Sleepiness and sleepiness perception in patients with Parkinson\u2019s disease: A clinical and electrophysiological study","volume":"42","author":"Bargiotas","year":"2019","journal-title":"Sleep"},{"key":"10.3233\/JPD-202425_ref11","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.smrv.2009.05.002","article-title":"Hyperarousal and insomnia: State of the science","volume":"14","author":"Bonnet","year":"2010","journal-title":"Sleep Med Rev"},{"key":"10.3233\/JPD-202425_ref12","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1016\/j.jns.2016.12.045","article-title":"Time for a strategy in night-time dopaminergic therapy? 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