{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T19:53:03Z","timestamp":1785009183676,"version":"3.55.0"},"reference-count":70,"publisher":"SAGE Publications","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JPD"],"published-print":{"date-parts":[[2021,10,12]]},"abstract":"<jats:p>Background: Mild cognitive impairment (MCI) in Parkinson\u2019s disease (PD) is considered a risk factor for PD with dementia (PDD). Verbal fluency tasks are widely used to assess executive function in PDD. However, in cases of PD with MCI (PD-MCI), the relative diagnostic accuracy of different qualitative verbal fluency measures and their related neural mechanisms remain unknown. Objective: This study aimed to investigate the relative diagnostic accuracy of qualitative (clustering and switching) verbal fluency strategies and their correlates with functional imaging in PD-MCI. Methods: Forty-five patients with PD (26 with MCI and 19 without MCI) and 25 healthy controls underwent comprehensive neurocognitive testing and resting-state functional magnetic resonance imaging. MCI in patients with PD was diagnosed according to established clinical criteria. The diagnostic accuracy of verbal fluency measures was determined via receiver operating characteristic analysis. Changes in brain functional connectivity between groups and across clinical measures were assessed using seed-to-voxel analyses. Results: Patients with PD-MCI generated fewer words and switched less frequently in semantic and phonemic fluency tasks compared to other groups. Switching in semantic fluency showed high diagnostic accuracy for PD-MCI and was associated with reduced functional connectivity in the salience network. Conclusion: Our results indicate that reduced switching in semantic fluency tasks is a sensitive and specific marker for PD-MCI. Qualitative verbal fluency deficits and salience network dysfunction represent early clinical changes observed in PD-MCI.<\/jats:p>","DOI":"10.3233\/jpd-202473","type":"journal-article","created":{"date-parts":[[2021,8,6]],"date-time":"2021-08-06T13:05:04Z","timestamp":1628255104000},"page":"2005-2016","source":"Crossref","is-referenced-by-count":8,"title":["Qualitative Deficits in Verbal Fluency in Parkinson\u2019s Disease with Mild Cognitive Impairment: A Clinical and Neuroimaging Study"],"prefix":"10.1177","volume":"11","author":[{"given":"Tomoya","family":"Hamada","sequence":"first","affiliation":[{"name":"Department of Neurology and Stroke Medicine, Yokohama City University Graduate School of Medicine, Yokohama, Kanagawa, Japan"},{"name":"Department of Speech-Language-Hearing Therapy, Japan Welfare Education College, Shinjuku-ku, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuichi","family":"Higashiyama","sequence":"additional","affiliation":[{"name":"Department of Neurology and Stroke Medicine, Yokohama City University Graduate School of Medicine, Yokohama, Kanagawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asami","family":"Saito","sequence":"additional","affiliation":[{"name":"Department of Neurology and Stroke Medicine, Yokohama City University Graduate School of Medicine, Yokohama, Kanagawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keisuke","family":"Morihara","sequence":"additional","affiliation":[{"name":"Department of Neurology and Stroke Medicine, Yokohama City University Graduate School of Medicine, Yokohama, Kanagawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramon","family":"Landin-Romero","sequence":"additional","affiliation":[{"name":"The University of Sydney, School of Psychology, Sydney, NSW, Australia"},{"name":"The University of Sydney, Brain & Mind Centre, Sydney, NSW, Australia"},{"name":"Australian Research Council Centre of Excellence in Cognition and its Disorders, Sydney, NSW, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitsuo","family":"Okamoto","sequence":"additional","affiliation":[{"name":"Department of Neurology and Stroke Medicine, Yokohama City University Graduate School of Medicine, Yokohama, Kanagawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katsuo","family":"Kimura","sequence":"additional","affiliation":[{"name":"Department of Neurology, Yokohama City University Medical Center Hospital, Yokohama, Kanagawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yousuke","family":"Miyaji","sequence":"additional","affiliation":[{"name":"Department of Neurology and Stroke Medicine, Yokohama City University Graduate School of Medicine, Yokohama, Kanagawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideto","family":"Joki","sequence":"additional","affiliation":[{"name":"Department of Neurology and Stroke Medicine, Yokohama City University Graduate School of Medicine, Yokohama, Kanagawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hitaru","family":"Kishida","sequence":"additional","affiliation":[{"name":"Department of Neurology, Yokohama City University Medical Center Hospital, Yokohama, Kanagawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Doi","sequence":"additional","affiliation":[{"name":"Department of Neurology and Stroke Medicine, Yokohama City University Graduate School of Medicine, Yokohama, Kanagawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naohisa","family":"Ueda","sequence":"additional","affiliation":[{"name":"Department of Neurology, Yokohama City University Medical Center Hospital, Yokohama, 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Disord"},{"key":"10.3233\/JPD-202473_ref5","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1017\/S1355617713000295","article-title":"Cognitive change in newly-diagnosed patients with Parkinson\u2019s disease: A 5-year follow-up study","volume":"19","author":"Broeders","year":"2013","journal-title":"J Int Neuropsychol Soc"},{"key":"10.3233\/JPD-202473_ref6","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1001\/jamaneurol.2013.2110","article-title":"Prognosis of mild cognitive impairment in early Parkinson disease: The Norwegian ParkWest study","volume":"70","author":"Pedersen","year":"2013","journal-title":"JAMA Neurol"},{"key":"10.3233\/JPD-202473_ref7","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1002\/mds.24893","article-title":"Diagnostic criteria for mild cognitive impairment in Parkinson\u2019s disease: Movement Disorder Society Task Force guidelines","volume":"27","author":"Litvan","year":"2012","journal-title":"Mov 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Disord"},{"key":"10.3233\/JPD-202473_ref11","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1136\/jnnp.2007.131045","article-title":"Parkinson\u2019s disease: Clinical features and diagnosis","volume":"79","author":"Jankovic","year":"2008","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.3233\/JPD-202473_ref12","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1037\/0894-4105.18.2.284","article-title":"A meta-analytic review of verbal fluency performance following focal cortical lesions","volume":"18","author":"Henry","year":"2004","journal-title":"Neuropsychology"},{"key":"10.3233\/JPD-202473_ref13","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1017\/S1355617706061078","article-title":"Role of frontal versus temporal cortex in verbal fluency as revealed by voxel-based lesion symptom mapping","volume":"12","author":"Baldo","year":"2006","journal-title":"J Int Neuropsychol 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Neurol"},{"key":"10.3233\/JPD-202473_ref32","doi-asserted-by":"crossref","first-page":"417","DOI":"10.3389\/fnagi.2017.00417","article-title":"Salience network and depressive severities in Parkinson\u2019s disease with mild cognitive impairment: A structural covariance network analysis","volume":"9","author":"Chang","year":"2018","journal-title":"Front Aging Neurosci"},{"key":"10.3233\/JPD-202473_ref33","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1017\/S1355617715000892","article-title":"Salience and default mode network coupling predicts cognition in aging and Parkinson\u2019s disease","volume":"22","author":"Putcha","year":"2016","journal-title":"J Int Neuropsychol Soc"},{"key":"10.3233\/JPD-202473_ref34","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1136\/jnnp.55.3.181","article-title":"Accuracy of clinical diagnosis of idiopathic Parkinson\u2019s disease: A clinico-pathological study of 100 cases","volume":"55","author":"Hughes","year":"1992","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.3233\/JPD-202473_ref35","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/0022-3956(75)90026-6","article-title":"\u201cMini-mental state\u201d. A practical method for grading the cognitive state of patients for the clinician","volume":"12","author":"Folstein","year":"1975","journal-title":"J Psychiatr Res"},{"key":"10.3233\/JPD-202473_ref36","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1212\/WNL.17.5.427","article-title":"Parkinsonism: Onset, progression, and mortality","volume":"17","author":"Hoehn","year":"1967","journal-title":"Neurology"},{"key":"10.3233\/JPD-202473_ref38","doi-asserted-by":"crossref","first-page":"2649","DOI":"10.1002\/mds.23429","article-title":"Systematic review of levodopa dose equivalency reporting in Parkinson\u2019s disease","volume":"25","author":"Tomlinson","year":"2010","journal-title":"Mov Disord"},{"key":"10.3233\/JPD-202473_ref39","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1111\/j.1532-5415.2005.53221.x","article-title":"The Montreal Cognitive Assessment, MoCA: A brief screening tool for mild cognitive impairment","volume":"53","author":"Nasreddine","year":"2005","journal-title":"J Am Geriatr Soc"},{"key":"10.3233\/JPD-202473_ref40","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1111\/j.1447-0594.2010.00585.x","article-title":"Brief screening tool for mild cognitive impairment in older Japanese: Validation of the Japanese version of the Montreal Cognitive Assessment","volume":"10","author":"Fujiwara","year":"2010","journal-title":"Geriatr Gerontol Int"},{"key":"10.3233\/JPD-202473_ref41","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1002\/1097-4679(198707)43:4<402::AID-JCLP2270430411>3.0.CO;2-E","article-title":"Relationships between parts A and B of the Trail Making Test","volume":"43","author":"Corrigan","year":"1987","journal-title":"J Clin Psychol"},{"key":"10.3233\/JPD-202473_ref42","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/0028-3932(74)90047-5","article-title":"The left frontal lobe of man and the suppression of habitual responses in verbal categorical behaviour","volume":"12","author":"Perret","year":"1974","journal-title":"Neuropsychologia"},{"key":"10.3233\/JPD-202473_ref43","unstructured":"Wechsler D (1987) Manual for theWechsler Memory Scale-Revised, The Psychological Corporation, San Antonio."},{"key":"10.3233\/JPD-202473_ref45","first-page":"206","article-title":"The test of copying a complex figure: A contribution to the study of perception and memory","volume":"30","author":"Osterrieth","year":"1944","journal-title":"Arch Psychol"},{"key":"10.3233\/JPD-202473_ref46","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1016\/0028-3932(89)90186-3","article-title":"Boston Naming Test in Alzheimer\u2019s disease","volume":"27","author":"Williams","year":"1989","journal-title":"Neuropsychologia"},{"key":"10.3233\/JPD-202473_ref48","unstructured":"Fujita K , Maekawa H , Dairoku K , Yamanaka K (2006) A Japanese version of theWAIS-III, Nihon Bunka Kagakusha, Tokyo."},{"key":"10.3233\/JPD-202473_ref49","unstructured":"Benton AL , Hamsher KD , Varney NR , Spreen O (1983) Judgment of line orientation, Oxford University Press, New York."},{"key":"10.3233\/JPD-202473_ref50","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1300\/J018v05n01_09","article-title":"9\/Geriatric Depression Scale (GDS)","volume":"5","author":"Yesavage","year":"1986","journal-title":"Clin Gerontol"},{"key":"10.3233\/JPD-202473_ref51","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1080\/07317115.2016.1199452","article-title":"A validity and reliability study of the Japanese version of the Geriatric Depression Scale 15 (GDS-15-J)","volume":"40","author":"Sugishita","year":"2017","journal-title":"Clin Gerontol"},{"key":"10.3233\/JPD-202473_ref52","doi-asserted-by":"crossref","first-page":"1625","DOI":"10.1161\/01.STR.24.11.1625","article-title":"Apathy following cerebrovascular lesions","volume":"24","author":"Starkstein","year":"1993","journal-title":"Stroke"},{"key":"10.3233\/JPD-202473_ref53","doi-asserted-by":"crossref","first-page":"2437","DOI":"10.1161\/01.STR.28.12.2437","article-title":"Poststroke apathy and regional cerebral blood flow","volume":"28","author":"Okada","year":"1997","journal-title":"Stroke"},{"key":"10.3233\/JPD-202473_ref54","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1002\/mds.26084","article-title":"Diagnosing PD-MCI by MDS Task Force criteria: How many and which neuropsychological tests?","volume":"30","author":"Goldman","year":"2015","journal-title":"Mov Disord"},{"key":"10.3233\/JPD-202473_ref55","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1002\/1097-0142(1950)3:1<32::AID-CNCR2820030106>3.0.CO;2-3","article-title":"Index for rating diagnostic tests","volume":"3","author":"Youden","year":"1950","journal-title":"Cancer"},{"key":"10.3233\/JPD-202473_ref56","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1002\/(SICI)1097-0193(1996)4:1<58::AID-HBM4>3.0.CO;2-O","article-title":"A unified statistical approach for determining significant signals in images of cerebral activation","volume":"4","author":"Worsley","year":"1996","journal-title":"Human Brain Mapp"},{"key":"10.3233\/JPD-202473_ref57","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1016\/j.parkreldis.2008.01.007","article-title":"Early neuropsychological detection and the characteristics of Parkinson\u2019s disease associated with mild dementia","volume":"14","author":"Song","year":"2008","journal-title":"Parkinsonism Relat Disord"},{"key":"10.3233\/JPD-202473_ref58","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1136\/jnnp-2013-305062","article-title":"Exploratory analysis of neuropsychological and neuroanatomical correlates of progressive mild 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