{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T19:32:23Z","timestamp":1790451143087,"version":"4.1.0"},"reference-count":8,"publisher":"SAGE Publications","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JPD"],"published-print":{"date-parts":[[2022,2,15]]},"abstract":"<jats:p>Subthalamic nucleus deep brain stimulation (STN DBS) is an established therapy for a subset of patients with Parkinson\u2019s disease, and the adjustment of DBS parameters is typically guided by the patients\u2019 rigidity and tremor. Although these cardinal symptoms remain relatively stable over time, progressive worsening of axial symptoms compromise motor function and quality of life. Because many patients report improvements in their global mobility after gait improvement, we have been adjusting DBS parameters during the long-term after surgery based on gait analysis. Here, we describe a practical strategy for troubleshooting gait problems in PD DBS patients by revising stimulation parameters through \u201chands-on\u201d programming, which can be a useful alternative approach for improving patients\u2019 outcomes after STN DBS.<\/jats:p>","DOI":"10.3233\/jpd-212771","type":"journal-article","created":{"date-parts":[[2021,12,17]],"date-time":"2021-12-17T11:57:51Z","timestamp":1639742271000},"page":"737-741","source":"Crossref","is-referenced-by-count":6,"title":["Troubleshooting Gait Problems in Parkinson\u2019s Disease Patients with Subthalamic Nucleus Deep Brain Stimulation"],"prefix":"10.1177","volume":"12","author":[{"given":"Thiago Gon\u00e7alves","family":"Guimar\u00e3es","sequence":"first","affiliation":[{"name":"Movement Disorders Center, Department of Neurology, University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rubens Gisbert","family":"Cury","sequence":"additional","affiliation":[{"name":"Movement Disorders Center, Department of Neurology, University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","reference":[{"key":"10.3233\/JPD-212771_ref1","doi-asserted-by":"crossref","first-page":"410","DOI":"10.3389\/fneur.2019.00410","article-title":"Deep brain stimulation programming for movement disorders: current concepts and evidence-based strategies","volume":"10","author":"Koeglsperger","year":"2019","journal-title":"Front Neurol"},{"key":"10.3233\/JPD-212771_ref2","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1038\/s41582-019-0145-9","article-title":"Long-term outcomes of deep brain stimulation in Parkinson disease","volume":"15","author":"Limousin","year":"2019","journal-title":"Nat Rev Neurol"},{"key":"10.3233\/JPD-212771_ref3","doi-asserted-by":"crossref","first-page":"1999","DOI":"10.1111\/j.1460-9568.2008.06167.x","article-title":"Bilateral coordination of walking and freezing of gait in Parkinson\u2019s disease","volume":"27","author":"Plotnik","year":"2008","journal-title":"Eur J Neurosci"},{"key":"10.3233\/JPD-212771_ref4","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1002\/mds.23583","article-title":"Modulation of gait coordination by subthalamic stimulation improves freezing of gait","volume":"26","author":"Fasano","year":"2011","journal-title":"Mov Disord"},{"key":"10.3233\/JPD-212771_ref5","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1186\/s40035-017-0083-7","article-title":"Effect of low versus high frequency stimulation on freezing of gait and other axial symptoms in Parkinson patients with bilateral STN DBS: a mini-review","volume":"6","author":"Xie","year":"2017","journal-title":"Transl Neurodegener"},{"key":"10.3233\/JPD-212771_ref6","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/j.brs.2016.02.004","article-title":"Programming deep brain stimulation for Parkinson\u2019s disease: The Toronto Western Hospital Algorithms","volume":"9","author":"Picillo","year":"2016","journal-title":"Brain Stimul"},{"key":"10.3233\/JPD-212771_ref7","doi-asserted-by":"crossref","first-page":"e786","DOI":"10.1016\/j.wneu.2019.06.223","article-title":"Interleaving stimulation in Parkinson disease: interesting to whom?","volume":"130","author":"Fran\u00e7a","year":"2019","journal-title":"World Neurosurg"},{"key":"10.3233\/JPD-212771_ref8","doi-asserted-by":"crossref","first-page":"659","DOI":"10.3389\/fneur.2019.00659","article-title":"New onset on-medication freezing ofgait after STN-DBS in Parkinson\u2019s disease","volume":"10","author":"Mei","year":"2019","journal-title":"Front Neurol"}],"container-title":["Journal of Parkinson's Disease"],"original-title":[],"link":[{"URL":"https:\/\/content.iospress.com\/download?id=10.3233\/JPD-212771","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T04:50:35Z","timestamp":1777611035000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.3233\/JPD-212771"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2,15]]},"references-count":8,"journal-issue":{"issue":"2"},"URL":"https:\/\/doi.org\/10.3233\/jpd-212771","relation":{},"ISSN":["1877-7171","1877-718X"],"issn-type":[{"value":"1877-7171","type":"print"},{"value":"1877-718X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,2,15]]}}}