{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T00:57:14Z","timestamp":1791593834476,"version":"4.3.4"},"reference-count":9,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2022,7,8]],"date-time":"2022-07-08T00:00:00Z","timestamp":1657238400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JPD"],"published-print":{"date-parts":[[2022,7,8]]},"abstract":"<jats:p>Digital health technologies (DHTs) have great potential for use as clinical trial outcomes; however, practical issues need to be addressed in order to maximise their benefit. We describe our experience of incorporating two DHTs as secondary\/exploratory outcome measures in PD STAT, a randomised clinical trial of simvastatin in people with Parkinson\u2019s disease. We found much higher rates of missing data in the DHTs than the traditional outcome measures, in particular due to technical and software difficulties. We discuss methods to address these obstacles in terms of protocol design, workforce training and data management.<\/jats:p>","DOI":"10.3233\/jpd-223162","type":"journal-article","created":{"date-parts":[[2022,4,22]],"date-time":"2022-04-22T11:33:53Z","timestamp":1650627233000},"page":"1605-1609","source":"Crossref","is-referenced-by-count":7,"title":["Challenges of Incorporating Digital Health Technology Outcomes in a Clinical Trial: Experiences from PD STAT"],"prefix":"10.1177","volume":"12","author":[{"given":"Jacob O.","family":"Day","sequence":"first","affiliation":[{"name":"Faculty of Health, University of Plymouth, Plymouth, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen","family":"Smith","sequence":"additional","affiliation":[{"name":"Department of Electronic Engineering, University of York, York, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alastair J.","family":"Noyce","sequence":"additional","affiliation":[{"name":"Preventive Neurology Unit, Wolfson Institute of Population Health, Queen Mary University of London, UK"},{"name":"Department of Clinical and Movement Neurosciences, UCL Institute of Neurology, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jane","family":"Alty","sequence":"additional","affiliation":[{"name":"Wicking Dementia Research and Education Centre, College of Health and Medicine, University of Tasmania, Hobart, Australia"},{"name":"Department of Neurology, Leeds Teaching Hospitals NHS Trust, Leeds, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alison","family":"Jeffery","sequence":"additional","affiliation":[{"name":"Peninsula Clinical Trials Unit, Faculty of Health, University of Plymouth, Plymouth, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca","family":"Chapman","sequence":"additional","affiliation":[{"name":"Peninsula Clinical 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