{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T09:56:51Z","timestamp":1777888611918,"version":"3.51.4"},"reference-count":30,"publisher":"SAGE Publications","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JPD"],"published-print":{"date-parts":[[2022,7,8]]},"abstract":"<jats:p>Patients with Parkinson\u2019s disease (PD) carrying variants in the Glucocerebrosidase (GBA) gene (GBA-PD) suffer from orthostatic symptoms more frequently than idiopathic PD patients (IPD). Systematic measurements of the blood pressure have not yet been performed. In the present study, a prospective analysis of 33 GBA-PD and 313 IPD patients was carried out. Systolic blood pressure upon changing from the supine to the upright position dropped more strongly in GBA-PD compared to IPD patients. Diastolic blood pressure and heart rate did not differ between groups. This study provides further evidence for a pronounced involvement of the autonomic nervous system in GBA-PD.<\/jats:p>","DOI":"10.3233\/jpd-223197","type":"journal-article","created":{"date-parts":[[2022,4,29]],"date-time":"2022-04-29T12:23:03Z","timestamp":1651234983000},"page":"1539-1544","source":"Crossref","is-referenced-by-count":9,"title":["Pronounced Orthostatic Hypotension in GBA-Related Parkinson\u2019s Disease"],"prefix":"10.1177","volume":"12","author":[{"given":"Tatiana","family":"Usnich","sequence":"first","affiliation":[{"name":"Institute of Neurogenetics, University of Luebeck, Luebeck, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"on behalf of the EPIPARK Study Group","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henrike","family":"Hanssen","sequence":"additional","affiliation":[{"name":"Institute of Neurogenetics, University of Luebeck, Luebeck, Germany"},{"name":"Department of 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