{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T17:25:09Z","timestamp":1790702709377,"version":"4.1.0"},"reference-count":29,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2023,12,13]],"date-time":"2023-12-13T00:00:00Z","timestamp":1702425600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Parkinson\u2019s Disease"],"published-print":{"date-parts":[[2023,12,16]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>A history of falls is the most established predictor of future falls in people with Parkinson\u2019s disease (PD). However, predicting a first fall remains challenging.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To assess whether experiencing difficulties putting on pants while standing is a viable predictor of future falling, and specifically a first fall, in persons with PD. We define this \u2018Pants-sign\u2019 as people who resort to putting on their pants only while seated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>264 persons with PD were included. Information on the Pants-sign, history of falls, disease severity (MDS-UPDRS part III), freezing of gait (N-FOGQ\u200a&gt;\u200a0), cognitive function (MoCA), self-reported disability (Schwab &amp; England scale), health-related quality of life (SF-12), Timed-Up-and-Go, and one-legged stance were determined at baseline and after one-year follow-up. The association between the Pants-sign and future falling was examined by univariate logistic regression analysis. A multivariate step-wise logistic regression with forward selection was employed to identify the strongest associations in the entire cohort and a sub-cohort of people without falls in the year prior to baseline.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The Pants-sign was univariably associated with a future fall (OR\u200a=\u200a2.406, 95% CI [1.313\u20134.409], p\u200a=\u200a0.004]), but was not an independent predictor in the multivariate logistic regression; predictors were higher MDS-UPDRS part III scores (OR\u200a=\u200a1.088, 95% CI [ 1.056\u20131.121 ], p\u200a&lt;\u200a0.001] and history of falls (OR\u200a=\u200a5.696, 95% CI [2.650\u201312.243], p\u22640.001]. For the sub-cohort of people without falls in the previous year ( n\u200a=\u200a189), the Pants-sign was not associated with future falls.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>The Pants-sign is simple to assess and is associated with future falling in PD but is not an independent predictor.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3233\/jpd-230353","type":"journal-article","created":{"date-parts":[[2023,12,15]],"date-time":"2023-12-15T11:19:50Z","timestamp":1702639190000},"page":"1321-1327","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["The \u2018Pants-Sign\u2019: A Predictor for Falling in\u00a0People with Parkinson\u2019s Disease?"],"prefix":"10.1177","volume":"13","author":[{"given":"Jamie A.F.","family":"Jansen","sequence":"first","affiliation":[{"name":"Radboud University Medical Center, Donders Institute for Brain, Cognition and Behavior, Department of Rehabilitation, Center of Expertise for Parkinson & Movement Disorders, Nijmegen, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anouk","family":"Tosserams","sequence":"additional","affiliation":[{"name":"Radboud University Medical Center, Donders Institute for Brain, Cognition and Behavior, Department of Rehabilitation, Center of Expertise for Parkinson & Movement Disorders, Nijmegen, The Netherlands"},{"name":"Radboud University Medical Center, Donders Institute for Brain, Cognition and Behavior, Department of Neurology, Center of Expertise for Parkinson & Movement Disorders, Nijmegen, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vivian G.M.","family":"Weerdesteyn","sequence":"additional","affiliation":[{"name":"Radboud University Medical Center, Donders Institute for Brain, Cognition and Behavior, Department of Rehabilitation, Center of Expertise for Parkinson & Movement Disorders, Nijmegen, The Netherlands"},{"name":"Department of Rehabilitation, Sint Maartenskliniek, Ubbergen, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bastiaan R.","family":"Bloem","sequence":"additional","affiliation":[{"name":"Radboud University Medical Center, Donders Institute for Brain, Cognition and Behavior, Department of Neurology, Center of Expertise for Parkinson & Movement Disorders, Nijmegen, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorik","family":"Nonnekes","sequence":"additional","affiliation":[{"name":"Radboud University Medical Center, Donders Institute for Brain, Cognition and Behavior, Department of Rehabilitation, Center of Expertise for Parkinson & Movement Disorders, Nijmegen, The Netherlands"},{"name":"Department of Rehabilitation, Sint Maartenskliniek, Ubbergen, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,12,13]]},"reference":[{"key":"ref001","first-page":"906274","volume":"2013","author":"Allen NE","year":"2013","journal-title":"Parkinsons Dis"},{"key":"ref002","doi-asserted-by":"publisher","DOI":"10.1177\/02692155231158565"},{"key":"ref003","doi-asserted-by":"publisher","DOI":"10.1007\/s004150170047"},{"key":"ref004","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199710303371806"},{"key":"ref005","doi-asserted-by":"publisher","DOI":"10.3233\/JPD-120113"},{"key":"ref006","doi-asserted-by":"publisher","DOI":"10.1016\/j.prdoa.2021.100089"},{"key":"ref007","first-page":"CD011574","volume":"6","author":"Allen NE","year":"2022","journal-title":"Cochrane Database Syst Rev"},{"key":"ref008","doi-asserted-by":"publisher","DOI":"10.1002\/mds.21598"},{"key":"ref009","doi-asserted-by":"publisher","DOI":"10.2217\/nmt.14.22"},{"key":"ref010","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.72.6.721"},{"key":"ref011","doi-asserted-by":"publisher","DOI":"10.1177\/1545968313508470"},{"key":"ref012","doi-asserted-by":"publisher","DOI":"10.3233\/NRE-2005-20304"},{"key":"ref013","doi-asserted-by":"publisher","DOI":"10.1002\/mds.27195"},{"key":"ref014","doi-asserted-by":"publisher","DOI":"10.1002\/mds.26742"},{"key":"ref015","doi-asserted-by":"publisher","DOI":"10.1186\/s12883-019-1394-3"},{"key":"ref016","doi-asserted-by":"publisher","DOI":"10.1016\/j.gaitpost.2009.07.108"},{"key":"ref017","doi-asserted-by":"publisher","DOI":"10.1002\/mds.22340"},{"key":"ref018","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.1991.tb01616.x"},{"key":"ref019","doi-asserted-by":"publisher","DOI":"10.14740\/jocmr1878w"},{"key":"ref020","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2005.53221.x"},{"key":"ref021","doi-asserted-by":"publisher","DOI":"10.1002\/mds.10248"},{"key":"ref022","doi-asserted-by":"publisher","DOI":"10.1097\/00005650-199603000-00003"},{"key":"ref023","first-page":"923493","volume":"2012","author":"Duncan RP","year":"2012","journal-title":"Parkinsons Dis"},{"key":"ref024","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2017.04.011"},{"key":"ref025","doi-asserted-by":"publisher","DOI":"10.1111\/psyg.12178"},{"key":"ref026","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2015.03.007"},{"key":"ref027","doi-asserted-by":"publisher","DOI":"10.3233\/JPD-150651"},{"key":"ref028","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3181e7b688"},{"key":"ref029","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2017.05.023"}],"container-title":["Journal of Parkinson\u2019s Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.3233\/JPD-230353","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.3233\/JPD-230353","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.3233\/JPD-230353","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T04:53:20Z","timestamp":1777611200000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.3233\/JPD-230353"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12,13]]},"references-count":29,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2023,12,16]]}},"alternative-id":["10.3233\/JPD-230353"],"URL":"https:\/\/doi.org\/10.3233\/jpd-230353","relation":{},"ISSN":["1877-7171","1877-718X"],"issn-type":[{"value":"1877-7171","type":"print"},{"value":"1877-718X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,12,13]]}}}