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We then detail three environmental toxicants that are likely among the main causes of Parkinson\u2019s disease\u2014 certain pesticides, the solvent trichloroethylene, and air pollution. All three environmental toxicants are ubiquitous, many affect mitochondrial functioning, and all can access humans via various routes, including inhalation and ingestion. We reach the hopeful conclusion that most of Parkinson\u2019s disease is thus preventable and that we can help to create a world where Parkinson\u2019s disease is increasingly rare.<\/jats:p>","DOI":"10.3233\/jpd-230357","type":"journal-article","created":{"date-parts":[[2024,1,12]],"date-time":"2024-01-12T12:19:48Z","timestamp":1705061988000},"page":"451-465","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":111,"title":["Parkinson\u2019s Disease Is Predominantly an Environmental Disease"],"prefix":"10.1177","volume":"14","author":[{"given":"E. 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