{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T17:05:12Z","timestamp":1778864712158,"version":"3.51.4"},"reference-count":70,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2024,7,15]],"date-time":"2024-07-15T00:00:00Z","timestamp":1721001600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Parkinson\u2019s Disease"],"published-print":{"date-parts":[[2024,7,23]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Research indicates that people with Parkinson\u2019s disease (PwPs) may experience challenges in both peripheral and central auditory processing, although findings are inconsistent across studies. Due to the diversity of auditory measures used, there is a need for standardized, replicable hearing assessments to clarify which aspects of audition are impacted in PWPs and whether they are linked to motor and non-motor symptoms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To characterize auditory processes and their possible alteration in PwPs. To address this, we collected a comprehensive set of standardized measures of audition using PART, a digital testing platform designed to facilitate replication. Additionally, we examined the relationship between auditory, cognitive, and clinical variables in PwPs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We included 44 PwPs and 54 age and education matched healthy controls. Assessments included detection of diotic and dichotic frequency modulation, temporal gaps, spectro-temporal broad-band modulation, and speech-on-speech masking.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>We found no statistically significant differences in auditory processing measures between PwPs and the comparison group (ps\u200a&gt;\u200a0.07). In PwPs, an auditory processing composite score showed significant medium size correlations with cognitive measures (0.39\u200a&lt;\u200ar&lt;0.41, ps\u200a&lt;\u200a0.02) and clinical variables of motor symptom severity, quality of life, depression, and caretaker burden (0.33\u200a&lt;\u200ar&lt;0.52, ps\u200a&lt;\u200a0.03).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>While larger datasets are needed to clarify whether PwPs experience more auditory difficulties than healthy controls, our results underscore the importance of considering auditory processing on the symptomatic spectrum of Parkinson\u2019s disease using standardized replicable methodologies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3233\/jpd-230458","type":"journal-article","created":{"date-parts":[[2024,7,19]],"date-time":"2024-07-19T11:54:19Z","timestamp":1721390059000},"page":"999-1013","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["A Characterization of Central Auditory Processing in Parkinson\u2019s Disease"],"prefix":"10.1177","volume":"14","author":[{"given":"E. Sebastian","family":"Lelo de Larrea-Mancera","sequence":"first","affiliation":[{"name":"Department of Psychology, Northeastern University, Boston, MA, USA"},{"name":"Laboratory of Cognitive and Clinical Neurophysiology, Instituto Nacional de Neurolog\u00eda y Neurocirug\u00eda Manuel Velasco Su\u00e1rez (INNNMVS), Mexico City, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erick I.","family":"Correa-Medina","sequence":"additional","affiliation":[{"name":"Laboratory of Cognitive and Clinical Neurophysiology, Instituto Nacional de Neurolog\u00eda y Neurocirug\u00eda Manuel Velasco Su\u00e1rez (INNNMVS), Mexico City, Mexico"},{"name":"Faculty of Psychology, Universidad Nacional Aut\u00f3noma de M\u00e9xico (UNAM), Mexico City, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katia","family":"Padilla-Bustos","sequence":"additional","affiliation":[{"name":"Laboratory of Cognitive and Clinical Neurophysiology, Instituto Nacional de Neurolog\u00eda y Neurocirug\u00eda Manuel Velasco Su\u00e1rez (INNNMVS), Mexico City, Mexico"},{"name":"Faculty of Psychology, Universidad Nacional Aut\u00f3noma de M\u00e9xico (UNAM), Mexico City, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diana Paulina","family":"Romero Ter\u00e1n","sequence":"additional","affiliation":[{"name":"Laboratory of Cognitive and Clinical Neurophysiology, Instituto Nacional de Neurolog\u00eda y Neurocirug\u00eda Manuel Velasco Su\u00e1rez (INNNMVS), Mexico City, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Jimena","family":"Hern\u00e1ndez-Medrano","sequence":"additional","affiliation":[{"name":"Clinical Laboratory of Neurodegenerative Diseases, INNNMVS, Mexico City, Mexico"},{"name":"Data Science Program, University of Maryland, Baltimore, MD, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gloria Itzel","family":"Cerda-Hern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Clinical Laboratory of Neurodegenerative Diseases, INNNMVS, Mexico City, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amin","family":"Cervantes-Arriaga","sequence":"additional","affiliation":[{"name":"Clinical Laboratory of Neurodegenerative Diseases, INNNMVS, Mexico City, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mayela","family":"Rodr\u00edguez-Violante","sequence":"additional","affiliation":[{"name":"Clinical Laboratory of Neurodegenerative Diseases, INNNMVS, Mexico City, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frederick J.","family":"Gallun","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Oregon Health & Science University, Portland, OR, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aaron 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