{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T10:25:13Z","timestamp":1777890313527,"version":"3.51.4"},"reference-count":11,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2017,8,23]],"date-time":"2017-08-23T00:00:00Z","timestamp":1503446400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Neonatal-Perinatal Medicine"],"published-print":{"date-parts":[[2017,10,17]]},"abstract":"<jats:p>We describe a neonate born with complex arrhythmias that included concurrent atrial and ventricular tachycardias. Genetic testing demonstrated a mutation in the TTN gene, which codes for titin, a large protein found in striated muscle sarcomeres. The complex arrhythmias were successfully treated with amiodarone and flecainide. The patient remains asymptomatic with normal biventricular function. We speculate that the complex arrhythmias and TTN gene mutation may be related.<\/jats:p>","DOI":"10.3233\/npm-16120","type":"journal-article","created":{"date-parts":[[2017,8,25]],"date-time":"2017-08-25T13:38:58Z","timestamp":1503668338000},"page":"343-346","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Neonatal complex arrhythmias possibly related to a TTN mutation"],"prefix":"10.1177","volume":"10","author":[{"given":"William N.","family":"Evans","sequence":"first","affiliation":[{"name":"Children\u2019s Heart Center Nevada, Las Vegas, NV, USA"},{"name":"Department of Pediatrics, Division of Cardiology, University of Nevada, Reno School of Medicine, Las Vegas, NV, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruben J.","family":"Acherman","sequence":"additional","affiliation":[{"name":"Children\u2019s Heart Center Nevada, Las Vegas, NV, USA"},{"name":"Department of Pediatrics, Division of Cardiology, University of Nevada, Reno School of Medicine, Las Vegas, NV, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ian H.","family":"Law","sequence":"additional","affiliation":[{"name":"Children\u2019s Heart Center Nevada, Las Vegas, NV, USA"},{"name":"Department of Pediatrics, Division of Cardiology, University of Iowa Carver College of Medicine, Iowa City, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicholas H.","family":"Von Bergen","sequence":"additional","affiliation":[{"name":"Children\u2019s Heart Center Nevada, Las Vegas, NV, USA"},{"name":"Department of Pediatrics, Division of Cardiology, University of Wisconsin-Madison, Madison, WI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ricardo A.","family":"Samson","sequence":"additional","affiliation":[{"name":"Children\u2019s Heart Center Nevada, Las Vegas, NV, USA"},{"name":"Department of Pediatrics, Division of Cardiology, University of Nevada, Reno School of Medicine, Las Vegas, NV, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Humberto","family":"Restrepo","sequence":"additional","affiliation":[{"name":"Children\u2019s Heart Center Nevada, Las Vegas, NV, USA"},{"name":"Department of Pediatrics, Division of Cardiology, University of Nevada, Reno School of Medicine, Las Vegas, NV, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2017,8,23]]},"reference":[{"key":"ref001","doi-asserted-by":"publisher","DOI":"10.1016\/j.cjca.2015.08.016"},{"key":"ref002","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1110186"},{"key":"ref003","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.110.005405"},{"key":"ref004","first-page":"295","volume":"102","author":"Marsiglia JD","year":"2014","journal-title":"Arq Bras Cardiol"},{"key":"ref005","doi-asserted-by":"publisher","DOI":"10.1038\/srep28356"},{"key":"ref006","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(01)01992-0"},{"key":"ref007","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2004.049049"},{"key":"ref008","doi-asserted-by":"publisher","DOI":"10.1139\/y11-070"},{"key":"ref009","doi-asserted-by":"publisher","DOI":"10.1016\/j.yjmcc.2016.01.014"},{"key":"ref010","first-page":"209","volume":"102","author":"Cummings S","year":"2011","journal-title":"Minerva Med"},{"key":"ref011","doi-asserted-by":"publisher","DOI":"10.1097\/HCO.0b013e32835b0a41"}],"container-title":["Journal of Neonatal-Perinatal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.3233\/NPM-16120","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.3233\/NPM-16120","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.3233\/NPM-16120","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T05:35:22Z","timestamp":1777613722000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.3233\/NPM-16120"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8,23]]},"references-count":11,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2017,10,17]]}},"alternative-id":["10.3233\/NPM-16120"],"URL":"https:\/\/doi.org\/10.3233\/npm-16120","relation":{},"ISSN":["1934-5798","1878-4429"],"issn-type":[{"value":"1934-5798","type":"print"},{"value":"1878-4429","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,8,23]]}}}