{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T12:08:44Z","timestamp":1785499724276,"version":"3.56.0"},"reference-count":42,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2017,12,26]],"date-time":"2017-12-26T00:00:00Z","timestamp":1514246400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Neonatal-Perinatal Medicine"],"published-print":{"date-parts":[[2017,12,26]]},"abstract":"<jats:sec>\n                    <jats:title>OBJECTIVE:<\/jats:title>\n                    <jats:p>We hypothesized that in-utero SSRI exposure affects Apgar scores and immediate post-delivery oxygen requirements.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>STUDY DESIGN:<\/jats:title>\n                    <jats:p>SSRI in-utero exposure was assessed retrospectively in preterm neonates \u2265 28 weeks gestation and term neonates. Primary outcome was Apgar &lt;7 at five minutes and delivery room oxygen requirements. Secondary endpoints included one-minute Apgar, length of stay, birth weight, and NICU admission.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>Fifty-one preterm and 117 term neonates were exposed to a SSRI; mostly to sertraline. Pre-term SSRI-exposed neonates had 4.1 times higher delivery room oxygen requirements. One minute Apgar &lt;7 was 3.5 times higher and NICU admission 5 times higher 95% CI (1.3\u201319) in SSRI-exposed term neonates. Higher doses of sertraline had associated adverse outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION:<\/jats:title>\n                    <jats:p>In-utero SSRI exposure was associated with increased neonatal care at birth, differences in Apgar scores compared with controls, and increased NICU admissions. Higher sertraline doses were associated with poorer outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3233\/npm-16133","type":"journal-article","created":{"date-parts":[[2017,12,29]],"date-time":"2017-12-29T11:58:39Z","timestamp":1514548719000},"page":"371-380","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":16,"title":["Effects of in-utero exposure to selective serotonin reuptake inhibitors and venlafaxine on term and preterm infants"],"prefix":"10.1177","volume":"10","author":[{"given":"A.N.","family":"Hogue","sequence":"first","affiliation":[{"name":"Department of Pharmacy Services, Hillcrest \u2013 Cleveland Clinic, Mayfield Heights, OH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.E.","family":"Temple-Cooper","sequence":"additional","affiliation":[{"name":"Department of Pharmacy Services, Hillcrest \u2013 Cleveland Clinic, Mayfield Heights, OH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Lagzdins","sequence":"additional","affiliation":[{"name":"Department of Pharmacy Services, Hillcrest \u2013 Cleveland Clinic, Mayfield Heights, OH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Worley","sequence":"additional","affiliation":[{"name":"Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Scwersenski","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Cleveland Clinic Children\u2019s Hospital, Cleveland, OH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Floyd","sequence":"additional","affiliation":[{"name":"Department of Pharmacy Services, Hillcrest \u2013 Cleveland Clinic, Mayfield Heights, OH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Saker","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Cleveland Clinic Children\u2019s Hospital, Cleveland, OH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2017,12,26]]},"reference":[{"issue":"112","key":"ref001","doi-asserted-by":"crossref","first-page":"e0144474","DOI":"10.1371\/journal.pone.0144474","volume":"10","author":"Zoega H","year":"2015","journal-title":"PLoS One"},{"key":"ref002","unstructured":"Centers for Disease Control and Prevention. 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