{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T10:25:47Z","timestamp":1777890347924,"version":"3.51.4"},"reference-count":21,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2016,3,12]],"date-time":"2016-03-12T00:00:00Z","timestamp":1457740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Neonatal-Perinatal Medicine"],"published-print":{"date-parts":[[2016,3,24]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND:<\/jats:title>\n                    <jats:p>Preeclampsia affects up to 10% of pregnancies worldwide and is one of the main causes of fetal morbidity and mortality. Although it has been linked to developmental delay, its long-term effects on neurologic development in children have yet to be sufficiently quantified.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>OBJECTIVES:<\/jats:title>\n                    <jats:p>To evaluate whether preeclampsia\u2019s severity and its obstetric management correlate to the degree of disability in these infants.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>MATERIALS AND METHOD:<\/jats:title>\n                    <jats:p>This is an observational and descriptive study performed on a population of 96 women who were diagnosed with preeclampsia at Hospital General Universitario Gregorio Mara\u00f1\u00f3n between 2007 and 2014, and their 111 children. To evaluate the mother, we gathered data pertaining to her medical history, renal function markers, and medical management of the preeclampsia. To assess the children, we collected fetal growth measurements, acute fetal distress markers and main diagnoses at birth. We used the Pediatric Evaluation of Disability Inventory in its computerized adaptive test version (PEDI-CAT) to study performance in the relevant areas, and the TNO-AZL Preschool children Quality of Life (TAPQOL) to estimate health-related quality of life.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>PEDI-CAT percentiles were consistently lower in the social\/cognitive domain than in other areas. Lower social\/cognitive percentiles were associated to both lower maternal IgG levels and presence of necrotizing enterocolitis during the neonatal period.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS:<\/jats:title>\n                    <jats:p>A connection between preeclampsia and poor social\/cognitive outcomes exists that warrants further research.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3233\/npm-16915065","type":"journal-article","created":{"date-parts":[[2016,3,25]],"date-time":"2016-03-25T12:14:55Z","timestamp":1458908095000},"page":"41-48","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Preeclampsia: Long-term effects on pediatric disability"],"prefix":"10.1177","volume":"9","author":[{"given":"C.","family":"Nicol\u00e1s","sequence":"first","affiliation":[{"name":"Hospital General Universitario Gregorio Mara\u00f1\u00f3n, Universidad Complutense de Madrid, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. Rodr\u00edguez","family":"Ben\u00edtez","sequence":"additional","affiliation":[{"name":"Nephrology Service, Hospital General Universitario Gregorio Mara\u00f1\u00f3n, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.O. Arroyo","family":"Ria\u00f1o","sequence":"additional","affiliation":[{"name":"Pediatric Rehabilitation Service, Hospital General Universitario Gregorio Mara\u00f1\u00f3n, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L. Matesanz","family":"Canencia","sequence":"additional","affiliation":[{"name":"Hospital General Universitario Gregorio Mara\u00f1\u00f3n, Universidad Complutense de Madrid, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Mercurio","sequence":"additional","affiliation":[{"name":"Hospital General Universitario Gregorio Mara\u00f1\u00f3n, Universidad Complutense de Madrid, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. Silva","family":"Fern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Hospital General Universitario Gregorio Mara\u00f1\u00f3n, Universidad Complutense de Madrid, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. S\u00e1nchez","family":"Luna","sequence":"additional","affiliation":[{"name":"Neonatology Service, Hospital General Universitario Gregorio Mara\u00f1\u00f3n, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. Tejedor","family":"Jorge","sequence":"additional","affiliation":[{"name":"Nephrology Service, Hospital General Universitario Gregorio Mara\u00f1\u00f3n, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2016,3,12]]},"reference":[{"key":"ref001","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2009.06.060"},{"key":"ref002","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1991.tb15339.x"},{"key":"ref003","doi-asserted-by":"publisher","DOI":"10.1016\/j.earlhumdev.2003.10.004"},{"key":"ref004","doi-asserted-by":"publisher","DOI":"10.1001\/jamapediatrics.2014.2645"},{"key":"ref005","doi-asserted-by":"publisher","DOI":"10.1081\/PRG-120016791"},{"key":"ref006","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2007.00552.x"},{"key":"ref007","doi-asserted-by":"publisher","DOI":"10.1002\/aur.42"},{"key":"ref008","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.23.6.514"},{"key":"ref009","doi-asserted-by":"publisher","DOI":"10.1002\/dneu.22052"},{"key":"ref010","doi-asserted-by":"publisher","DOI":"10.1007\/s10803-009-0903-4"},{"key":"ref011","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2011.02.032"},{"key":"ref012","doi-asserted-by":"publisher","DOI":"10.1001\/jamapediatrics.2013.2904"},{"key":"ref013","doi-asserted-by":"publisher","DOI":"10.1111\/jcpp.12351"},{"key":"ref014","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2010-1036"},{"key":"ref015","doi-asserted-by":"publisher","DOI":"10.1016\/j.clp.2012.12.009"},{"key":"ref016","doi-asserted-by":"publisher","DOI":"10.1007\/s11920-012-0337-0"},{"key":"ref017","doi-asserted-by":"publisher","DOI":"10.3109\/09638288.2011.607217"},{"key":"ref018","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijnurstu.2010.09.004"},{"key":"ref019","doi-asserted-by":"publisher","DOI":"10.3109\/01942638.2011.606260"},{"key":"ref020","doi-asserted-by":"publisher","DOI":"10.5014\/ajot.2012.004218"},{"key":"ref021","doi-asserted-by":"publisher","DOI":"10.1177\/1362361313480277"}],"container-title":["Journal of Neonatal-Perinatal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.3233\/NPM-16915065","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.3233\/NPM-16915065","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.3233\/NPM-16915065","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T05:35:56Z","timestamp":1777613756000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.3233\/NPM-16915065"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,3,12]]},"references-count":21,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016,3,24]]}},"alternative-id":["10.3233\/NPM-16915065"],"URL":"https:\/\/doi.org\/10.3233\/npm-16915065","relation":{},"ISSN":["1934-5798","1878-4429"],"issn-type":[{"value":"1934-5798","type":"print"},{"value":"1878-4429","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,3,12]]}}}