{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T21:33:39Z","timestamp":1778103219094,"version":"3.51.4"},"reference-count":22,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2019,10,8]],"date-time":"2019-10-08T00:00:00Z","timestamp":1570492800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Neonatal-Perinatal Medicine"],"published-print":{"date-parts":[[2020,4,10]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND:<\/jats:title>\n                    <jats:p>Renal pelvic dilatation (RPD) is a frequent finding in fetal ultrasound. The aim of the study is to correlate the prenatally detected moderate and severe pyelectasis with the postnatal outcome.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS:<\/jats:title>\n                    <jats:p>A retrospective analysis involving 90 cases of prenatally detected moderate and severe RPD referred to our prenatal diagnosis centre with 18 months of urological follow-up. Prenatal ultrasound was correlated with postnatal renal function, assessed by plasmatic creatinine and\/or renal scintigraphy performed before surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>Cases were divided between two groups according to postnatal management: group A including 35 newborns (38.9%) that needed surgical treatment and group B with 55 patients (61.1%) who were managed conservatively. The group A presented higher median RPD (18\u200amm, IQR 12\u201325\u200amm) compared to the group B (11\u200amm, IQR 10\u201314\u200amm). The most common anomaly detected within group A was pelvi-ureteric junction (PUI) obstruction (43%). Within group B 32 cases (58%) showed spontaneous resolution of hydronephrosis during postnatal follow up. In case of moderate pyelectasis the risk of postnatal surgery was 25% and raised to 60% for severe RPD. In our study, 29 newborns showed pathologic scintigraphies: 25 required surgery while 4 did not find indication for surgery due to ipsilateral renal function irreversible damage. 6 patients had high creatinine level (&gt;0.6\u200amg\/dl). 35 cases out of 90 (39%) developed monolateral irreversible renal function impairment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION:<\/jats:title>\n                    <jats:p>Moderate and severe RPD are often correlated with postnatal renal damage, therefore a close multidisciplinary follow-up is required. Prenatal scanning is highly predictive of postnatal outcome and can address properly the prenatal counseling.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3233\/npm-180071","type":"journal-article","created":{"date-parts":[[2019,10,8]],"date-time":"2019-10-08T12:41:59Z","timestamp":1570538519000},"page":"91-96","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Moderate and severe fetal pyelectasis: Correlation between prenatal aspects and postnatal outcome"],"prefix":"10.1177","volume":"13","author":[{"given":"C.","family":"Loardi","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Prenatal Diagnosis Unit, ASST Spedali Civili Brescia, University of Brescia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Signorelli","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Prenatal Diagnosis Unit, ASST Spedali Civili Brescia, University of Brescia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Gregorini","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Prenatal Diagnosis Unit, ASST Spedali Civili Brescia, University of Brescia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Marella","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Prenatal Diagnosis Unit, ASST Spedali Civili Brescia, University of Brescia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Torri","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, ASST Spedali Civili Brescia, University of Brescia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. Mario","family":"Zambelloni","sequence":"additional","affiliation":[{"name":"Department of Neonatology, ASST Spedali Civili Brescia, University of Brescia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"U.","family":"Omodei","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, ASST Spedali Civili Brescia, University of Brescia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Odicino","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, ASST Spedali Civili Brescia, University of Brescia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2019,10,8]]},"reference":[{"key":"ref001","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpobgyn.2014.01.009"},{"key":"ref002","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.2001.00333.x"},{"key":"ref003","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmg.2005.02.003"},{"key":"ref004","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpurol.2010.02.205"},{"key":"ref005","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2006.03.079"},{"key":"ref006","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2006-0120"},{"key":"ref007","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2004.04.023"},{"key":"ref008","doi-asserted-by":"publisher","DOI":"10.1080\/01443610500041446"},{"key":"ref009","doi-asserted-by":"publisher","DOI":"10.1016\/j.pcl.2012.05.003"},{"key":"ref010","doi-asserted-by":"publisher","DOI":"10.1002\/pd.2893"},{"key":"ref011","doi-asserted-by":"publisher","DOI":"10.1007\/s11934-009-0023-x"},{"key":"ref012","doi-asserted-by":"publisher","DOI":"10.1007\/s004670050716"},{"key":"ref013","doi-asserted-by":"publisher","DOI":"10.1046\/j.1464-410X.1998.0810s2039.x"},{"issue":"2","key":"ref014","first-page":"F135","volume":"18","author":"Jawson MS","year":"1999","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"key":"ref015","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.160.3.3526402"},{"key":"ref016","doi-asserted-by":"publisher","DOI":"10.3109\/14767058.2014.939065"},{"key":"ref017","doi-asserted-by":"publisher","DOI":"10.1002\/pd.4472"},{"key":"ref018","doi-asserted-by":"publisher","DOI":"10.1002\/uog.935"},{"key":"ref019","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-005-2100-9"},{"key":"ref020","doi-asserted-by":"publisher","DOI":"10.1097\/00008480-200104000-00009"},{"key":"ref021","doi-asserted-by":"publisher","DOI":"10.1097\/00003081-199706000-00008"},{"key":"ref022","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-015-2687-1"}],"container-title":["Journal of Neonatal-Perinatal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.3233\/NPM-180071","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.3233\/NPM-180071","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.3233\/NPM-180071","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T05:36:48Z","timestamp":1777613808000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.3233\/NPM-180071"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10,8]]},"references-count":22,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,4,10]]}},"alternative-id":["10.3233\/NPM-180071"],"URL":"https:\/\/doi.org\/10.3233\/npm-180071","relation":{},"ISSN":["1934-5798","1878-4429"],"issn-type":[{"value":"1934-5798","type":"print"},{"value":"1878-4429","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,10,8]]}}}