{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T10:26:48Z","timestamp":1777890408032,"version":"3.51.4"},"reference-count":10,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2018,8,23]],"date-time":"2018-08-23T00:00:00Z","timestamp":1534982400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Neonatal-Perinatal Medicine"],"published-print":{"date-parts":[[2018,12,21]]},"abstract":"<jats:p>We report a 3-month-old male with Down syndrome (DS), prolonged jaundice and poor weight gain, that showed biliary lithiasis and undiagnosed congenital hypothyroidism (CH).<\/jats:p>\n                  <jats:p>CH should be considered in DS, especially in presence of gastrointestinal symptoms or malformations. Clinicians should be aware of the increased risk of gallstones in hypothyroid children with DS, even in neonatal age.<\/jats:p>","DOI":"10.3233\/npm-181","type":"journal-article","created":{"date-parts":[[2018,8,24]],"date-time":"2018-08-24T13:58:33Z","timestamp":1535119113000},"page":"423-425","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Neonatal cholelithiasis in Down syndrome: Is hypothyroidism involved? A case-report"],"prefix":"10.1177","volume":"11","author":[{"given":"F.","family":"Ricci","sequence":"first","affiliation":[{"name":"Department of Health Sciences, Anna Meyer Children\u2019s University Hospital, University of Florence, Florence, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Stagi","sequence":"additional","affiliation":[{"name":"Department of Health Sciences, Anna Meyer Children\u2019s University Hospital, University of Florence, Florence, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Messa","sequence":"additional","affiliation":[{"name":"Department of Health Sciences, Anna Meyer Children\u2019s University Hospital, University of Florence, Florence, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"de Martino","sequence":"additional","affiliation":[{"name":"Department of Health Sciences, Anna Meyer Children\u2019s University Hospital, University of Florence, Florence, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2018,8,23]]},"reference":[{"key":"ref001","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2007.09.045"},{"key":"ref002","first-page":"6","volume":"7","author":"Holmes G","year":"2014","journal-title":"Gastroenterol Hepatol Bed Bench"},{"key":"ref003","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3468(99)90011-8"},{"key":"ref004","doi-asserted-by":"publisher","DOI":"10.1097\/00008480-199706000-00017"},{"key":"ref005","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2012.04.037"},{"key":"ref006","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320460537"},{"key":"ref007","doi-asserted-by":"publisher","DOI":"10.1136\/adc.85.3.242"},{"key":"ref008","doi-asserted-by":"publisher","DOI":"10.17511\/ijpr.2016.i03.10"},{"key":"ref009","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2007-1316"},{"key":"ref010","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(97)70544-1"}],"container-title":["Journal of Neonatal-Perinatal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.3233\/NPM-181","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.3233\/NPM-181","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.3233\/NPM-181","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T05:37:06Z","timestamp":1777613826000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.3233\/NPM-181"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8,23]]},"references-count":10,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2018,12,21]]}},"alternative-id":["10.3233\/NPM-181"],"URL":"https:\/\/doi.org\/10.3233\/npm-181","relation":{},"ISSN":["1934-5798","1878-4429"],"issn-type":[{"value":"1934-5798","type":"print"},{"value":"1878-4429","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,8,23]]}}}