{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T10:26:54Z","timestamp":1777890414890,"version":"3.51.4"},"reference-count":23,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2018,4,16]],"date-time":"2018-04-16T00:00:00Z","timestamp":1523836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Neonatal-Perinatal Medicine"],"published-print":{"date-parts":[[2018,4,16]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND:<\/jats:title>\n                    <jats:p>The objective of this study was to determine factors associated with long-term intermittent positive pressure ventilation (IPPV) in extremely preterm infants.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS:<\/jats:title>\n                    <jats:p>Study setting was a ten bed pod (SBP) part of the Level IV all referral NICU, dedicated to the care of infants born at &lt;27 weeks and which utilizes a protocol-driven approach to care. All admissions to the SBP from 2005 to 2011 were included if admitted in the first week of life and alive at 56 days of age.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>There were 210 patients and 35% were on IPPV for \u226556 days (for the purposes of this study defined as long-term IPPV). Long-term IPPV patients were born earlier, had lower birth weight, were admitted later, and more likely to come from a level III NICU. LTV patients were more likely to have a PDA ligation, receive dopamine, receive TPN longer, and receive supplemental oxygen at 36 weeks PMA. In logistic regression modeling transfer from another Level III NICU (OR 3.7, 95% CI 1.5\u20139.2, p\u200a=\u200a0.006) and recieveing dopamine (OR 3.1, 95% CI 1.5\u20136.3, p\u200a=\u200a0.002) were associated with long-term IPPV.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS:<\/jats:title>\n                    <jats:p>In this cohort of infants born at &lt;27 weeks gestation 35% were on long term IPPV. There are identifiable factors known on admission and occurring during the NICU stay that are associated with long-term IPPV.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3233\/npm-181711","type":"journal-article","created":{"date-parts":[[2018,4,17]],"date-time":"2018-04-17T11:56:03Z","timestamp":1523966163000},"page":"29-35","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Factors associated with long-term mechanical ventilation in extremely preterm infants"],"prefix":"10.1177","volume":"11","author":[{"given":"Lina","family":"Yossef","sequence":"first","affiliation":[{"name":"Ohio Perinatal Research Network, Center for Perinatal Research, Research Institute at Nationwide Children\u2019s Hospital, Columbus, OH, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edward G.","family":"Shepherd","sequence":"additional","affiliation":[{"name":"Small Baby ICU, Nationwide Children\u2019s Hospital, Columbus, OH, USA"},{"name":"Department of Pediatrics, The Ohio State University, Columbus, OH, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susan","family":"Lynch","sequence":"additional","affiliation":[{"name":"Small Baby ICU, Nationwide Children\u2019s Hospital, Columbus, OH, USA"},{"name":"Department of Pediatrics, The Ohio State University, Columbus, OH, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristina M.","family":"Reber","sequence":"additional","affiliation":[{"name":"Small Baby ICU, Nationwide Children\u2019s Hospital, Columbus, OH, USA"},{"name":"Department of Pediatrics, The Ohio State University, Columbus, OH, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leif D.","family":"Nelin","sequence":"additional","affiliation":[{"name":"Ohio Perinatal Research Network, Center for Perinatal Research, Research Institute at Nationwide Children\u2019s Hospital, Columbus, OH, USA"},{"name":"Small Baby ICU, Nationwide Children\u2019s Hospital, Columbus, OH, USA"},{"name":"Department of Pediatrics, The Ohio State University, Columbus, OH, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2018,4,16]]},"reference":[{"key":"ref001","doi-asserted-by":"publisher","DOI":"10.1097\/MOP.0b013e3283423e6b"},{"key":"ref002","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2010.01846.x"},{"key":"ref003","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM196702162760701"},{"key":"ref004","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.physiol.67.040403.102229"},{"key":"ref005","doi-asserted-by":"publisher","DOI":"10.1097\/MOP.0b013e328346577f"},{"key":"ref006","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.163.7.2011060"},{"key":"ref007","doi-asserted-by":"publisher","DOI":"10.1513\/AnnalsATS.201504-218OC"},{"key":"ref008","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa072788"},{"key":"ref009","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2009.01413.x"},{"key":"ref010","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0911783"},{"key":"ref011","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2013-1880"},{"key":"ref012","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2013-3442"},{"key":"ref013","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2005-0249"},{"key":"ref014","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-013-2016-5"},{"key":"ref015","doi-asserted-by":"publisher","DOI":"10.1038\/jp.2013.75"},{"key":"ref016","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2009.01563.x"},{"key":"ref017","doi-asserted-by":"publisher","DOI":"10.3233\/NPM-2011-2728"},{"key":"ref018","doi-asserted-by":"publisher","DOI":"10.3233\/NPM-2012-55511"},{"key":"ref019","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2009-2959"},{"key":"ref020","doi-asserted-by":"publisher","DOI":"10.1016\/j.earlhumdev.2011.12.013"},{"key":"ref021","doi-asserted-by":"publisher","DOI":"10.1053\/j.semperi.2013.01.006"},{"key":"ref022","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2009.771"},{"key":"ref023","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.23020"}],"container-title":["Journal 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